Changes in the Rate of Human Papilloma Virus Serotypes after Vaccine Implementation: A Descriptive Study

A. Gallardo, Montserrat de la Torre Serrano, Lone Nielsen, Alejandro Pascual Martín, Concepción Millana de Ynes, María Jesús González Fuensalida, Patricia Barreiro Sanabria, Eva Rodríguez Escudero, D. López, Aranzazu Gómez Rodríguez, Rosa Rodero Villanueva, M. J. Aceñero
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Abstract

Background: The main objective of this study is to describe the rate of the different serotypes of HPV in cervical cytologies and biopsies in three different periods: 2002-2006 (prior to the implementation of the vaccination programs in Spain), 2009-2011 (shortly after this implementation) and 2020 (al-most 15 years after introduction of the vaccine) at a single hospital. Methods: This is an observational, descriptive, retrospective study based on the review of the results of the determination of the HPV serotype using the commercial kit (Genomica ® ; PharmaMar LTD) in cervical liquid-based cytologies and biopsies at a single large tertiary hospital, Hospital Clínico San Carlos, in Madrid, Spain. We have collected the data from three different time periods: 2002-2006; 2009-2011, and 2020 to try to understand the potential changes associated with
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接种疫苗后人乳头瘤病毒血清型率的变化:一项描述性研究
背景:本研究的主要目的是描述在三个不同时期:2002-2006年(西班牙实施疫苗接种计划之前),2009-2011年(实施后不久)和2020年(引入疫苗后最多15年)在一家医院的宫颈细胞学和活检中不同血清型HPV的比率。方法:这是一项观察性、描述性、回顾性研究,基于对使用商业试剂盒(Genomica®;在西班牙马德里的一家大型三级医院Clínico圣卡洛斯医院进行宫颈液体细胞学检查和活组织检查。我们收集了三个不同时期的数据:2002年至2006年;2009-2011年和2020年试图了解与之相关的潜在变化
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