Fluorescein Diacetate Staining- A Strategy of Laboratories Capacity Building for Efficient Management of Mycobacterium Infections Treatment in Resource Limited Settings

Abstract

Mycobacterium tuberculosis complex and non-tuberculosis mycobacterium are still caused serious problems of public health around the world, mainly in resource limited settings. The emergence of drug resistant, failure and relapse of mycobacterium infections treatment made the need of efficient and cost-effective tools for treatment monitoring. In resource limited settings with poor facilities, the transfer and implementation by National Tuberculosis Programs of fluorescein diacetate vitality staining could be used as an alternative method of mycobacteria culture for drug therapy monitoring in district level. We described in this review the potential use of fluorescein diacetate staining in the monitoring of infectious disease caused by mycobacterium strains.