Pseudoangiomatous Stromal Hyperplasia-Case Report of a Rare Breast Tumor in a Premenarchal Girl

Abstract

ABS TRACT Pseudoangiomatous stromal hyperplasia is a rare benign breast neoplasm. The exact prevalence of this condition is unknown. According to the literature, it is an extremely uncommon disease in adolescent patients, especially when presenting with a giant mass causing significant breast enlargement. The clinical management of pseudoangiomatous stromal hyperplasia continues to be a controversial issue, however, surgical treatment remains the most accepted when there is an important mass-effect. We report the case of a 12-year-old premenarchal female, referred to our hospital with complaints of a rapidly enlarging left breast mass, of 12cm in diameter, causing a significant breast asym- metry. The ultrasonographic findings were unspecific. The core needle biopsy of the mass was consistent with pseudoangiomatous stromal hyperplasia, consequently, successful surgical excision was performed. This case illustrates a particularly unusual presentation of pseudoan- giomatous stromal hyperplasia in a premenarchal adolescent patient, that should be taken into consideration in the differential diagnosis of abrupt breast enlargement.