Diagnosis and therapeutic management updated on intrathoracic schwannoma

S. A. O. Júnior, R. Silva, Jéssica Siebra Macário de Brito, T. E. V. Lemos, Bárbara Monitchelly Fernandes Chaves, Amália Cinthia Menezes Rêgo, I. Araújo-Filho
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Abstract

Background: Schwannoma is a benign neoplasm derived from Schwann cells. It is usually located in the intracranial nerves, however intrathoracic presentation is possible, leading to compression of adjacent structures and symptoms. The absence of results from physical examination and the presence of mild symptoms (or absence) common to other diseases makes the diagnosis challenging, usually accomplished through imaging. Treatment consists of surgical resection by thoracotomy or thoracoscopy. This study aimed to review this subject with an emphasis on the diagnostic and therapeutic approaches currently available. Method: Articles were selected by searching the Scopus, Scielo, PubMed and Web of Science databases using the keywords: schwannoma, neurinoma, neurilemmoma, nerve tissue neoplasm, thoracotomy, thoracoscopy and mediastinal neoplasms. Results: Intrathoracic schwannoma often presents as asymptomatic and is identified during routine imaging tests. The recommended treatment is surgical resection by thoracoscopy or thoracotomy.
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胸内神经鞘瘤的诊断和治疗管理进展
背景:神经鞘瘤是源于雪旺细胞的良性肿瘤。它通常位于颅内神经,但也可能出现在胸内,导致邻近结构受压和症状。体格检查无结果和其他疾病常见的轻微症状的存在(或缺失)使诊断具有挑战性,通常通过影像学完成。治疗方法包括开胸或胸腔镜手术切除。本研究旨在回顾这一主题,重点是目前可用的诊断和治疗方法。方法:检索Scopus、Scielo、PubMed、Web of Science数据库,检索关键词:神经鞘瘤、神经鞘瘤、神经鞘瘤、神经组织肿瘤、开胸手术、胸腔镜、纵隔肿瘤。结果:胸内神经鞘瘤通常表现为无症状,可在常规影像学检查中发现。推荐的治疗方法是胸腔镜或开胸手术切除。
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