Curative management of malignant left-sided colorectal obstruction

Wen-Shen Lee, J. Kong, P. Carne, S. Bell, S. Warrier
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Abstract

Left-sided malignant colonic obstruction remains a challenging surgical problem despite recent advances. We aim to provide a concise overview of the relevant surgical options for this condition in the curative setting. A literature search of MedLine, PubMed, and Embase was performed to elucidate the latest evidence in the management of malignant left-sided colorectal obstruction, focusing on the risks and benefits of each approach and the appropriate patient selection. Primary resection and anastomosis are the intervention of choice for low-risk patients in the curative setting. Delayed resection with a bridge to surgery should be considered in unwell patients requiring medical optimization. While stenting has gained popularity, the risk of stent perforation carries a poor prognosis and must be carefully considered. Hartmann's procedure should be considered in high-risk elderly patients. Subtotal colectomy is preferred over segmental colectomy when there is extensive proximal colon damage but results in more frequent bowel actions postoperatively.
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恶性左侧结直肠梗阻的治疗
尽管最近取得了进展,但左侧恶性结肠梗阻仍然是一个具有挑战性的手术问题。我们的目的是提供一个简明的概述,相关的手术选择,为这种情况下的治疗设置。通过MedLine、PubMed和Embase的文献检索,阐明了恶性左侧结直肠梗阻治疗的最新证据,重点分析了每种方法的风险和益处以及适当的患者选择。初级切除和吻合是低风险患者在治疗环境中的首选干预措施。对于身体不适、需要医疗优化的患者,应考虑延迟切除,然后再进行手术。虽然支架置入术越来越受欢迎,但支架穿孔的风险预后不良,必须仔细考虑。老年高危患者应考虑采用Hartmann手术。当近端结肠有广泛损伤时,结肠次全切除术优于节段性结肠切除术,但术后大便更频繁。
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