Gold Nanoparticles Incorporated with Cyclodextrins and Its Applications

Fahad Alanazi, D. Salah
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引用次数: 2

Abstract

Cyclodextrins are naturally oligosaccharides which had cyclic glucopyrano-side units even if six units to form α-cyclodextrin (α-CD), seven units β-cyclodextrin (β-CD) or eight units γ-cyclodextrin (γ-CD) and some other derivatives. It has a truncated cone shape with a hydrophobic cavity and a hydrophilic from the external surface of cyclodextrins. Gold nanoparticles incorporated with cyclodextrins enhanced optical and electrical properties of the resulting conjugates, due to the gold nanoparticles’ unique physical and chemical properties because of their surface plasmon resonance. Here is a review of gold nanoparticles/cyclodextrin’s different applications including sensing, antimicrobial effect, and their variable medical/pharmaceutical applications. Generally, gold nanoparticles and cyclodextrin conjugates showed developed and pronounced advantages due to their biocompatibility and enhanced physical and electric properties.
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含环糊精的金纳米颗粒及其应用
环糊精是一种天然的低聚糖,具有环葡核苷侧单位,即使有6个单位可以形成α-环糊精(α-CD)、7个单位的β-环糊精(β-CD)或8个单位的γ-环糊精(γ-CD)及其衍生物。它具有截断的圆锥体形状,具有疏水腔和环糊精外表面的亲水性。与环糊精结合的金纳米颗粒由于其表面等离子体共振而具有独特的物理和化学性质,从而增强了所得到的共轭物的光学和电学性能。本文综述了金纳米颗粒/环糊精的不同应用,包括传感、抗菌作用及其各种医疗/制药应用。总的来说,金纳米颗粒和环糊精缀合物由于其生物相容性和增强的物理和电学性能而显示出发展和显著的优势。
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