{"title":"Partially Oxidized Polydiphenylamine for Sensitive Electrochemical Determination of Ceftazidime","authors":"K. Zarei, M. Lesani","doi":"10.4152/pea.202004229","DOIUrl":null,"url":null,"abstract":"This work reports the development of a glassy carbon electrode (GCE), modified with an oxidized poly diphenylamine/multi-walled carbon nanotubes-β-cyclodextrin (OPDPA /MWCNT-β-CD) composite film, for ceftazidime determination. The OPDPA/MWCNT-β-CD film surface morphology was investigated using field emission scanning electron microscopy (FESEM) and cyclic voltammetry (CV). Ceftazidime was adsorbed onto the OPDPA/MWCNT-β-CD, at open circuit, for 240 seconds, and then oxidized in acidic media. The electrochemistry of ceftazidime oxidation was investigated using cyclic voltammetry and differential pulse voltammetry (DPV). Under optimum conditions, the peak current linearly increased with ceftazidime concentration, in the range of 5×10 M to 1×10 M. The obtained detection limit was 1.0×10 M. This sensor was employed for ceftazidime determination in the biological and pharmaceutical samples.","PeriodicalId":20334,"journal":{"name":"Portugaliae Electrochimica Acta","volume":"38 1","pages":"229-241"},"PeriodicalIF":1.1000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Portugaliae Electrochimica Acta","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4152/pea.202004229","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ELECTROCHEMISTRY","Score":null,"Total":0}
引用次数: 2
Abstract
This work reports the development of a glassy carbon electrode (GCE), modified with an oxidized poly diphenylamine/multi-walled carbon nanotubes-β-cyclodextrin (OPDPA /MWCNT-β-CD) composite film, for ceftazidime determination. The OPDPA/MWCNT-β-CD film surface morphology was investigated using field emission scanning electron microscopy (FESEM) and cyclic voltammetry (CV). Ceftazidime was adsorbed onto the OPDPA/MWCNT-β-CD, at open circuit, for 240 seconds, and then oxidized in acidic media. The electrochemistry of ceftazidime oxidation was investigated using cyclic voltammetry and differential pulse voltammetry (DPV). Under optimum conditions, the peak current linearly increased with ceftazidime concentration, in the range of 5×10 M to 1×10 M. The obtained detection limit was 1.0×10 M. This sensor was employed for ceftazidime determination in the biological and pharmaceutical samples.
期刊介绍：
Portugaliae Electrochimica Acta is a bi-monthly Journal published by the Portuguese Electrochemical Society since 1983. Portugaliae Electrochimica Acta publishes original papers, brief communications, reviews and letters concerned with every aspect of theory and practice of electrochemistry, as well as articles in which topics on history, science policy, education, etc. in the electrochemical field (teaching or research) may be discussed.
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