Yu Lei, Dehua Zhang, Yang Liu, Guanghui Tian, Hongguang Ge
{"title":"Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide","authors":"Yu Lei, Dehua Zhang, Yang Liu, Guanghui Tian, Hongguang Ge","doi":"10.4236/JCPT.2014.43017","DOIUrl":null,"url":null,"abstract":"A pair of new anticancer nucleosides based on 1,2,4-triazole \nnucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide \nhave been synthesized, and have given the corresponding products in excellent \nyields. Its structures and conformations were confirmed by single crystal X-ray \ndiffraction.","PeriodicalId":64440,"journal":{"name":"结晶过程及技术期刊(英文)","volume":"04 1","pages":"135-139"},"PeriodicalIF":0.0000,"publicationDate":"2014-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"结晶过程及技术期刊(英文)","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.4236/JCPT.2014.43017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
A pair of new anticancer nucleosides based on 1,2,4-triazole
nucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide
have been synthesized, and have given the corresponding products in excellent
yields. Its structures and conformations were confirmed by single crystal X-ray
diffraction.