Use of psychopharmaceuticals during COVID-19 treatment

M. Milosavljević, O. Vuković
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Abstract

No specific cure has been found since the beginning of the COVID-19 pandemic. In the treatment of infection caused by SARS-CoV-2 virus, therapeutic protocols include drugs of different groups: antiviral drugs, antibodies, antibiotics, anti-inflammatory drugs, etc. It can be expected that a certain number of patients who are receiving therapy with psychopharmacotherapy will get sick from COVID-19, but we also know that the infection itself has certain psychological manifestations. Due to the above, the use of psychopharmacotherapy together with other drugs in the therapy of COVID-19 is sometimes unavoidable. Co-administering these drugs has to be with caution due to the potential prolongation of the QTc interval, drug interactions at the CYP enzyme level, and the associated potential for agranulocytosis.
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COVID-19治疗期间精神药物的使用
自2019冠状病毒病大流行开始以来,还没有找到具体的治疗方法。在SARS-CoV-2病毒感染的治疗中,治疗方案包括不同类别的药物:抗病毒药物、抗体、抗生素、抗炎药等。可以预见,在接受精神药物治疗的患者中,会有一定数量的人感染新冠病毒,但我们也知道,感染本身有一定的心理表现。因此,精神药物治疗与其他药物联合使用有时是不可避免的。由于QTc间隔的潜在延长、CYP酶水平上的药物相互作用以及相关的粒细胞缺乏症的可能性,联合使用这些药物必须谨慎。
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