Frailty and mortality in long-term care facilities for older people in Brazil: a survival analysis

A. R. B. D. Fonseca, P. Silva, T. Carvalho, Millene Abo Arrage, Sara Regina da Silva Duarte, A. L. Selegatto, A. P. Valle, P. V. Boas
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引用次数: 1

Abstract

OBJECTIVES: To investigate the effect of frailty on 1-year mortality in long term-care facility (LTCF) residents. METHODS: This was a prospective cohort study with survival analysis of 209 participants living in 15 Brazilian LTCFs. Data on chronic diseases, age, sex, medication use, dependence in activities of daily living (ADLs; Katz index), and frailty (FRAIL scale) were collected at baseline, and death after 1 year was the outcome measure. Kaplan-Meier estimate and log-rank test were used to analyze the survival of residents. RESULTS: In the initial assessment, 65.07 of the residents were women, and the median age was 82 (interquartile range, 71–88) years, with 55% being over 80 years old. Overall, 88% had 2 or more diseases, 59.81% were using 5 or more medications, 42.11% were considered frail, 34.92% pre-frail, and 22.97% robust, and 69.94% were dependent in 3 or more ADLs. During the 12-month follow-up, 19.61% of the residents (n=41) died. In the survival analysis for death, there was a statistically significant association with frailty (p=0.03) and dependence in ADLs (p=0.04). CONCLUSIONS: In this population of LTCF residents, frailty and functional dependence were associated with death.
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巴西老年人长期护理机构的虚弱和死亡率:生存分析
目的:探讨衰弱对长期护理机构(LTCF)住院患者1年死亡率的影响。方法:这是一项前瞻性队列研究,对生活在15个巴西ltcf中的209名参与者进行了生存分析。关于慢性病、年龄、性别、药物使用、日常生活活动依赖性(ADLs)的数据;在基线时收集卡茨指数(Katz index)和虚弱程度(虚弱量表),并以1年后死亡为结局指标。采用Kaplan-Meier估计和log-rank检验分析居民的生存状况。结果:初评时,65.07名居民为女性,年龄中位数为82岁(四分位间距71 ~ 88岁),其中80岁以上的占55%。总体而言,88%患有2种或2种以上疾病,59.81%使用5种或5种以上药物,42.11%被认为虚弱,34.92%虚弱前期,22.97%健壮,69.94%依赖3种或3种以上adl。在12个月的随访中,有19.61%的居民(n=41)死亡。在死亡的生存分析中,与衰弱(p=0.03)和adl依赖性(p=0.04)有统计学意义的关联。结论:在LTCF患者中,虚弱和功能依赖与死亡相关。
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审稿时长
24 weeks
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