I. O. Savelyeva, Yulia S. Bortnevskaya, A. Y. Usanev, N. A. Bragina, A. Mironov, A. Ignatova, A. Feofanov, K. A. Zhdanova
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引用次数: 3
Abstract
In this work, cationic meso-arylsubstituted porphyrin and its Zn(II) complex were synthesized. The compounds were characterized by multinuclear NMR spectroscopy, electronic spectroscopy and ESI-mass spectrometry. The photodynamic activity of the porphyrins was studied in relation to S. aureus bacteria and their biofilms. Application of polymeric micelles of Pluronic F-127 as nanosized delivery vehicles supports high antimicrobial photodynamic activity of the synthesized porphyrins. The influence of the central metal atom on the dark and light-induced toxicity of the synthesized compounds was revealed. non-irradiated control plate. Statistics . The results were considered statistically signifi cant with a 95 % confidence level. All experiments were repeated at least 3 times with comparable results. Statistical analysis was performed using the Student’s coefficient. Results are presented as mean ± SD.
期刊介绍：
The journal is a forum for the specialists investigating macroheterocyclic compounds. It publishes original experimental and theoretical works (full papers and short communications) and reviews on synthesis, structural characterization, physical and coordination chemistry as well as practical application of macroheterocycles.
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