Anosmia and dysgeusia among corona virus disease (COVID-19) patients- A review

A. Jeppu, Nurshafiqa Binti Rohaidi, Khairunnisa Binti Mohamad Sukri, Ganegeshwaran Rajan, K. Kumar
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Abstract

COVID-19 is a viral infection of the respiratory tract presenting with fever, cough and fatigue. Absence of specific symptoms makes diagnosis and control of transmission of this disease a challenging task.Some recent studies have reported smell and taste dysfunction in COVID 19 patients. However, little is known about the prevalence and pathogenesis of these two symptoms with conflicting reports on the duration of these symptoms, recovery rate as well as the prognosis of patients who have anosmia and /or dysgeusia. To seek answers, a literature review on this topic from databases like PubMed, Clinical Key, Science Direct, Scopus and Google Scholar was conducted. The objective of this review was to further examine the prevalence of the smell and taste dysfunction in COVID-19 patients, explorethe pathophysiology for the occurrence of these two symptoms and evaluate its prognostic value.It was observed that olfactory and gustatory dysfunction was more prevalent among COVID-19 patients who belonged to younger age group and among females. Patients who presented with anosmia and dysgeusia as their main symptoms had lesser severity of the COVID-19 infection when compared to patients without these symptoms indicating that patients with chemosensory dysfunction have good prognosis.
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冠状病毒病(COVID-19)患者的嗅觉缺失和认知障碍
COVID-19是一种呼吸道病毒感染,表现为发烧、咳嗽和疲劳。由于缺乏具体症状,诊断和控制该病的传播是一项具有挑战性的任务。最近的一些研究报告了COVID - 19患者的嗅觉和味觉功能障碍。然而,对这两种症状的患病率和发病机制知之甚少,关于这些症状的持续时间、恢复率以及嗅觉缺失和/或嗅觉障碍患者的预后的报道相互矛盾。为了寻找答案,我们从PubMed、Clinical Key、Science Direct、Scopus和谷歌Scholar等数据库中对这一主题进行了文献综述。本综述的目的是进一步了解COVID-19患者嗅觉和味觉功能障碍的患病率,探讨这两种症状发生的病理生理机制,并评估其预后价值。观察到嗅觉和味觉功能障碍在年轻年龄组和女性患者中更为普遍。以嗅觉缺失和语言障碍为主要症状的患者与无这些症状的患者相比,新冠肺炎感染的严重程度较轻,表明化学感觉功能障碍患者预后良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
International Journal of Medical Toxicology and Legal Medicine
International Journal of Medical Toxicology and Legal Medicine Medicine-Pathology and Forensic Medicine
CiteScore
1.10
自引率
0.00%
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0
期刊介绍: To disseminate scientific information in relation to medico-legal work among all desirous medical , research and legal persons. To create literature in the medico-legal , toxicology , forensic sciences , forensic medicine, crime scene investigation and other related scientific fields. To promote scientific temperament in the nation building. To enhance research and writing of scientific articles and experiences. To develop creativity and positive outlook among concerned professionals.
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