Clinicopathological Spectrum of Salivary Gland Lesions - A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh

Sanuvada Vijay Rama Raja Sekhar, Regidi Swathi Ratnam, B. Gouthami, B. R. Chandra
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Abstract

Introduction: The salivary glands are subjected to various pathological conditions ranging from simple inflammation to most complex malignant lesions. Majority of these lesions can be diagnosed by simple histopathological examination. But, as these salivary gland lesions are not common, the incidence of these varies in different geographic locations. Aim: To study the spectrum of different salivary gland lesions and demographic data in a tertiary care hospital serving North East coastal area of Andhra Pradesh. Materials and Methods: This was a retrospective study conducted in Great Eastern Medical School and Hospital,Srikakulam, Andhra Pradesh, India. Total of 85 salivary gland lesions were analyzed for a period of 4 years (December 2015 to November 2019). From the records of Histopathology, Department of Pathology, data was retrieved. Typing of the salivary gland tumours were done using sections stained with Hematoxylin and Eosin (H&E). All the cases were analysed and divided according to the demographics and histological type. Descriptive statistics were used and data was tabulated in frequency and percentages. Results: A total of 85 salivary gland lesions were studied, of which 14 (16%) were non-neoplastic and 71 (84%) were neoplastic in nature. Among the neoplastic lesions, 56 (66%) were benign and 15 (18%) were malignant. There was slight male preponderance with a ratio of M:F=1.3:1. Majority of the tumours occurred in parotid gland (73), followed by submandibular gland (7) and minor salivary glands (5). All the tumours were classified and graded according to World Health Organization (WHO), while Brandwein Grading System was followed for mucoepidermoid carcinoma. Pleomorphic adenoma was the most frequent benign tumour and mucoepidermoid carcinoma was the most common malignant tumour. Conclusion: Though benign salivary gland tumours are more frequently encountered in the present study, malignant salivary gland tumours are not uncommon.
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唾液腺病变的临床病理谱-来自安得拉邦三级保健研究所的回顾性研究
唾液腺遭受各种病理条件,从简单的炎症到最复杂的恶性病变。大多数病变可通过简单的组织病理学检查诊断。但是,由于这些唾液腺病变并不常见,这些发病率在不同的地理位置有所不同。目的:研究安得拉邦东北沿海地区某三级医院不同唾液腺病变的频谱和人口统计数据。材料和方法:本研究是在印度安得拉邦Srikakulam的大东方医学院和医院进行的回顾性研究。分析了4年(2015年12月至2019年11月)共85例唾液腺病变。从病理科组织病理学记录中检索数据。用苏木精和伊红(H&E)染色切片对涎腺肿瘤进行分型。根据人口统计学和组织学类型对所有病例进行分析和分类。采用描述性统计,数据以频率和百分比制成表格。结果:共85例唾液腺病变,其中非肿瘤性病变14例(16%),肿瘤性病变71例(84%)。其中良性56例(66%),恶性15例(18%)。男性有轻微优势,比例为M:F=1.3:1。大多数肿瘤发生在腮腺(73例),其次是颌下腺(7例)和少量唾液腺(5例)。所有肿瘤均按照世界卫生组织(WHO)分类和分级,粘液表皮样癌采用Brandwein分级系统。多形性腺瘤是最常见的良性肿瘤,粘液表皮样癌是最常见的恶性肿瘤。结论:虽然良性涎腺肿瘤在本研究中更为常见,但恶性涎腺肿瘤也不罕见。
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审稿时长
12 weeks
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