Kubra Atciyurt, Cihan Heybeli, Lee Smith, Nicola Veronese, Pinar Soysal
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引用次数: 0
Abstract
Objectives: Adequate hydration is essential for the maintenance of physiological functions. Older adults may not be able to maintain adequate hydration, which is often not recognized. Our aim was to investigate the prevalence, risk factors and clinical implications of dehydration in older adults.
Methods: This cross-sectional study included 964 older adults in one geriatric outpatient clinic in Turkey. Dehydration was defined as a calculated [1,86 × (Na+K)+1,15×glucose+urea +14] plasma osmolarity of ≥ 295 mOsm/L. Clinical characteristics and measures of comprehensive geriatric assessments of patients with dehydration and normohydration were compared. Predictors of dehydration were assessed using logistic regression analysis.
Results: Mean age was 79.9 ± 7.7 years, (71.7% female). The prevalence of dehydration was 31%. Female patients, diabetes mellitus (DM), chronic renal failure (CKD), a higher risk of falling (based on Timed Up and Go test), probable sarcopenia, dependence based on basic and instrumental daily living activities (BADL and IADL) were more common in the dehydrated group (p < 0.05). After adjusting for age and gender, dependency on BADL and IADL, the risk of falling were still higher in the dehydrated group (p < 0.05). There were significant relationships between dehydration and risk of falling (OR 1.38, 95% CI 1.00-1.90; p < 0.05), after adjustment for age, gender, DM, CKD.
Conclusion: Dehydration is common among older adults and is associated with a dependency, probable sarcopenia, and an increased risk of falling. Screening for dehydration and taking preventive measures may be beneficial in avoiding the negative consequences associated with dehydration.
目的:充足的水合作用对维持生理功能至关重要。老年人可能无法保持足够的水合作用,这通常是不被认识到的。我们的目的是调查老年人脱水的患病率、危险因素和临床意义。方法:这项横断面研究包括土耳其一家老年门诊诊所的964名老年人。脱水定义为计算[1.86 × (Na+K)+1,15×葡萄糖+尿素+14]血浆渗透压 ≥ 295 mOsm/L。比较了脱水和正常水合患者的临床特征和老年综合评估措施。使用逻辑回归分析评估脱水的预测因素。结果:平均年龄79.9岁 ± 7.7 年龄(71.7%为女性)。脱水发生率为31%。女性患者、糖尿病(DM)、慢性肾功能衰竭(CKD)、跌倒风险较高(基于Timed Up and Go测试)、可能的少肌症、基于基本和工具性日常生活活动的依赖性(BADL和IADL)在脱水组中更常见(p p p 结论:脱水在老年人中很常见,与依赖性、可能的少肌症和跌倒风险增加有关。筛查脱水并采取预防措施可能有助于避免与脱水相关的负面后果。
期刊介绍:
Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine primarily publishes papers on clinical medicine, clinical chemistry, pathology and molecular biology, provided they describe results which contribute to our understanding of clinical problems or describe new methods applicable to clinical investigation. Readership includes physicians, pathologists, pharmacists and physicians working in non-academic and academic hospitals, practicing internal medicine and its subspecialties.