Kidney Biopsy Corner: Amyloidosis.

Glomerular diseases Pub Date : 2023-09-08 eCollection Date: 2023-01-01 DOI:10.1159/000533195
Laura E Biederman, Alana D Dasgupta, Darren E Dreyfus, Tibor Nadasdy, Anjali A Satoskar, Sergey V Brodsky
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Abstract

Amyloidosis is an infiltrative disease caused by misfolded proteins depositing in tissues. Amyloid infiltrates the kidney in several patterns. There are, as currently described by the International Society of Amyloidosis, 14 types of amyloid that can involve the kidney, and these types may have different locations or clinical settings. Herein we report a case of AA amyloidosis occurring in a 24-year-old male with a history of intravenous drug abuse and provide a comprehensive review of different types of amyloids involving the kidney.

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肾脏活检角:淀粉样变性。
淀粉样变性是一种由错误折叠的蛋白质沉积在组织中引起的浸润性疾病。淀粉样蛋白以几种方式浸润肾脏。正如国际淀粉样变性学会目前所描述的,有14种类型的淀粉样蛋白可能涉及肾脏,这些类型可能有不同的位置或临床环境。在此,我们报告了一例AA淀粉样变性病例,该病例发生在一名有静脉注射药物滥用史的24岁男性身上,并对涉及肾脏的不同类型的淀粉样变性进行了全面综述。
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