The fluorosis conundrum: bridging the gap between science and public health.

IF 3.2 4区 医学 Q1 Pharmacology, Toxicology and Pharmaceutics Toxicology Mechanisms and Methods Pub Date : 2024-02-01 Epub Date: 2024-01-29 DOI:10.1080/15376516.2023.2268722
Sachindra Kumar, Vishal Chhabra, Manmeet Mehra, Saranya K, Harish Kumar B, Smita Shenoy, Ravindra Shantakumar Swamy, Krishna Murti, K Sreedhara Ranganath Pai, Nitesh Kumar
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Abstract

Fluorosis, a chronic condition brought on by excessive fluoride ingestion which, has drawn much scientific attention and public health concern. It is a complex and multifaceted issue that affects millions of people worldwide. Despite decades of scientific research elucidating the causes, mechanisms, and prevention strategies for fluorosis, there remains a significant gap between scientific understanding and public health implementation. While the scientific community has made significant strides in understanding the etiology and prevention of fluorosis, effectively translating this knowledge into public health policies and practices remains challenging. This review explores the gap between scientific research on fluorosis and its practical implementation in public health initiatives. It suggests developing evidence-based guidelines for fluoride exposure and recommends comprehensive educational campaigns targeting the public and healthcare providers. Furthermore, it emphasizes the need for further research to fill the existing knowledge gaps and promote evidence-based decision-making. By fostering collaboration, communication, and evidence-based practices, policymakers, healthcare professionals, and the public can work together to implement preventive measures and mitigate the burden of fluorosis on affected communities. This review highlighted several vital strategies to bridge the gap between science and public health in the context of fluorosis. It emphasizes the importance of translating scientific evidence into actionable guidelines, raising public awareness about fluoride consumption, and promoting preventive measures at individual and community levels.

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氟中毒难题:弥合科学与公共卫生之间的差距。
氟中毒是一种由过量摄入氟引起的慢性疾病,引起了科学界和公众的广泛关注。这是一个复杂而多方面的问题,影响着全世界数百万人。尽管几十年来的科学研究阐明了氟中毒的原因、机制和预防策略,但在科学理解和公共卫生实施之间仍然存在重大差距。尽管科学界在理解氟中毒的病因和预防方面取得了重大进展,但将这些知识有效地转化为公共卫生政策和实践仍然具有挑战性。这篇综述探讨了氟中毒的科学研究与其在公共卫生倡议中的实际实施之间的差距。它建议制定基于证据的氟化物暴露指南,并建议针对公众和医疗保健提供者开展全面的教育活动。此外,它强调需要进一步研究,以填补现有的知识空白,促进循证决策。通过促进合作、沟通和循证实践,政策制定者、医疗保健专业人员和公众可以共同实施预防措施,减轻氟中毒对受影响社区的负担。这篇综述强调了在氟中毒背景下弥合科学与公共卫生之间差距的几个重要策略。它强调了将科学证据转化为可操作的指导方针、提高公众对氟化物消费的认识以及在个人和社区层面推广预防措施的重要性。
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来源期刊
CiteScore
6.60
自引率
3.10%
发文量
66
审稿时长
6-12 weeks
期刊介绍: Toxicology Mechanisms and Methods is a peer-reviewed journal whose aim is twofold. Firstly, the journal contains original research on subjects dealing with the mechanisms by which foreign chemicals cause toxic tissue injury. Chemical substances of interest include industrial compounds, environmental pollutants, hazardous wastes, drugs, pesticides, and chemical warfare agents. The scope of the journal spans from molecular and cellular mechanisms of action to the consideration of mechanistic evidence in establishing regulatory policy. Secondly, the journal addresses aspects of the development, validation, and application of new and existing laboratory methods, techniques, and equipment. A variety of research methods are discussed, including: In vivo studies with standard and alternative species In vitro studies and alternative methodologies Molecular, biochemical, and cellular techniques Pharmacokinetics and pharmacodynamics Mathematical modeling and computer programs Forensic analyses Risk assessment Data collection and analysis.
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