Disability-adjusted life years due to leptospirosis in Monaragala District of Sri Lanka

IF 2.4 2区 农林科学 Q3 INFECTIOUS DISEASES Zoonoses and Public Health Pub Date : 2023-11-02 DOI:10.1111/zph.13088
A. M. U. P. Kumari, J. Vidanapathirana, J. Amarasekara, L. Karunanayake
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Abstract

Leptospirosis is a zoonotic infection with significant morbidity and mortality. As an occupational disease, it has become a global concern due to its disease burden in endemic countries and rural areas. The aim of this study was to assess disease burden in terms of Disability-adjusted life years (DALYs) of leptospirosis.A hospital-based descriptive cross-sectional study was conducted using 450 clinically diagnosed leptospirosis patients admitted to base and above hospitals in Monaragala District, Sri Lanka, using a pre-tested interviewer-administered questionnaire. The patients were followed up until normal day-to-day life after discharge. Estimation of DALYs was done using laboratory-confirmed leptospirosis patients. Leptospirosis disease burden in Monaragala District was 44.9 DALYs per 100,000 population, which includes 33.18 Years of life losts and 10.9 YLDs. The incidence of leptospirosis in Monaragala District during the study period was 59.8 per 100,000 population, and the case fatality rate (CFR) was 1.5% and 75% of deaths were among males.The disease burden of leptospirosis in Monaragala District was significantly high and urgent efforts to control and prevent leptospirosis should be a priority.

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斯里兰卡Monaragala区因钩端螺旋体病导致的残疾调整寿命。
钩端螺旋体病是一种人畜共患传染病,具有显著的发病率和死亡率。作为一种职业病,由于其在流行国家和农村地区的疾病负担,它已成为全球关注的问题。本研究的目的是根据钩端螺旋体病的残疾调整生命年(DALYs)来评估疾病负担。一项基于医院的描述性横断面研究使用了450名临床诊断的钩端螺旋体病患者,这些患者入住斯里兰卡莫纳拉加拉区的基层及以上医院,使用了一份预先测试的访谈者管理的问卷。对患者进行随访,直到出院后的日常生活正常。使用实验室确诊的钩端螺旋体病患者评估DALY。Monaragala区的钩端螺旋体病负担为每100000人44.9 DALY,其中包括33.18 生命损失年数和10.9 YLD。研究期间,莫纳拉加拉区的钩端螺旋体病发病率为每100000人59.8例,病死率(CFR)为1.5%,75%的死亡病例为男性。莫纳拉加拉区钩端螺旋体病的疾病负担非常高,应优先采取紧急措施控制和预防钩端螺旋虫病。
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来源期刊
Zoonoses and Public Health
Zoonoses and Public Health 医学-传染病学
CiteScore
5.30
自引率
4.20%
发文量
115
审稿时长
6-12 weeks
期刊介绍: Zoonoses and Public Health brings together veterinary and human health researchers and policy-makers by providing a venue for publishing integrated and global approaches to zoonoses and public health. The Editors will consider papers that focus on timely collaborative and multi-disciplinary research in zoonoses and public health. This journal provides rapid publication of original papers, reviews, and potential discussion papers embracing this collaborative spirit. Papers should advance the scientific knowledge of the sources, transmission, prevention and control of zoonoses and be authored by scientists with expertise in areas such as microbiology, virology, parasitology and epidemiology. Articles that incorporate recent data into new methods, applications, or approaches (e.g. statistical modeling) which enhance public health are strongly encouraged.
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