Laboratory method to induce state boredom increases impulsive choice in people who use cocaine and controls.

IF 2.7 3区 医学 Q2 PSYCHOLOGY, CLINICAL American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2023-11-03 DOI:10.1080/00952990.2023.2248544
Thomas Chao, McWelling Todman, Richard W Foltin, Suzette M Evans, Gillinder Bedi
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Abstract

Background: Impulsive choice is associated with both cocaine use and relapse. Little is known about the influence of transient states on impulsive choice in people who use cocaine (PWUC).Objective: This study investigated the direct effects of induced boredom on impulsive choice (i.e., temporal discounting) in PWUC relative to well-matched community controls.Methods: Forty-one PWUC (≥1× cocaine use in past 3 months; 7 females) and 38 demographically matched controls (5 females) underwent two experimental conditions in counterbalanced order. Temporal discounting was assessed immediately after a standardized boredom induction task (peg-turning) and a self-selected video watched for the same duration (non-boredom). Subjective mood state and perceived task characteristics were assessed at baseline, during experimental manipulations, and after the choice task.Results: PWUC and controls were well matched on sex, age, and socioeconomic status. Groups were also similar in reported use of drugs other than cocaine, except for recent cigarette and alcohol use (PWUC > controls). As expected, peg-turning increased boredom in the sample overall, with higher boredom reported during peg-turning than the video (p < .001, η2p = .20). Participants overall exhibited greater impulsive choice after boredom than non-boredom (p = .028, η2p = .07), with no preferential effects in PWUC (p > .05, BF01 = 2.9).Conclusion: Experimentally induced boredom increased state impulsivity irrespective of cocaine use status - in PWUC and carefully matched controls - suggesting a broad link between boredom and impulsive choice. This is the first study to show that transient boredom directly increases impulsive choice. Data support a viable laboratory method to further parse the effects of boredom on impulsive choice.

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实验室诱导状态无聊的方法增加了使用可卡因和对照品的人的冲动选择。
背景:冲动性选择与可卡因使用和复发有关。关于短暂状态对可卡因使用者冲动选择的影响,我们知之甚少。目的:本研究调查了与匹配良好的社区对照相比,可卡因使用者的诱导无聊对冲动选择(即时间折扣)的直接影响。方法:41名PWUC(≥1×过去3年可卡因使用量) 月;7名女性)和38名人口统计学匹配的对照组(5名女性)按平衡顺序接受了两种实验条件。在标准化的无聊诱导任务(翻钉)和观看相同持续时间的自选视频(非无聊)后,立即评估时间折扣。主观情绪状态和感知任务特征在基线、实验操作期间和选择任务后进行评估。结果:PWUC和对照组在性别、年龄和社会经济地位方面匹配良好。除了最近吸烟和饮酒外,各组报告的可卡因以外的药物使用情况也相似(PWUC>对照组)。不出所料,翻钉会增加样本的无聊感,翻钉过程中的无聊感高于视频(p 2便士 = .20) 。总体而言,参与者在无聊之后表现出比非无聊更大的冲动选择(p = .028,η2p = .07),在PWUC中没有优先效应(p > .05,BF01 = 2.9)。结论:在PWUC和精心匹配的对照组中,无论可卡因使用状态如何,实验诱导的无聊都会增加状态冲动性,这表明无聊与冲动选择之间存在广泛联系。这是第一项研究表明,短暂的无聊会直接增加冲动的选择。数据支持一种可行的实验室方法来进一步分析无聊对冲动选择的影响。
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来源期刊
CiteScore
4.70
自引率
3.70%
发文量
68
期刊介绍: The American Journal of Drug and Alcohol Abuse (AJDAA) is an international journal published six times per year and provides an important and stimulating venue for the exchange of ideas between the researchers working in diverse areas, including public policy, epidemiology, neurobiology, and the treatment of addictive disorders. AJDAA includes a wide range of translational research, covering preclinical and clinical aspects of the field. AJDAA covers these topics with focused data presentations and authoritative reviews of timely developments in our field. Manuscripts exploring addictions other than substance use disorders are encouraged. Reviews and Perspectives of emerging fields are given priority consideration. Areas of particular interest include: public health policy; novel research methodologies; human and animal pharmacology; human translational studies, including neuroimaging; pharmacological and behavioral treatments; new modalities of care; molecular and family genetic studies; medicinal use of substances traditionally considered substances of abuse.
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