Single and double injection paravertebral block comparison in reduction mammaplasty cases: a randomized controlled study.

Anesthesia and pain medicine Pub Date : 2023-10-01 Epub Date: 2023-10-30 DOI:10.17085/apm.23029
Vecih Anil Ozonur, Emine Aysu Salviz, Nukhet Sivrikoz, Erol Kozanoglu, Soner Karaali, Huru Ceren Gokduman, Hacer Polat, Ufuk Emekli, Mehmet Kamil Tugrul, Mukadder Orhan-Sungur
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Abstract

Background: This study compares the analgesic effects and dermatomal blockade distributions of single and double injection bilateral thoracic paravertebral block (TPVB) techniques in patients undergoing reduction mammaplasty.

Methods: After obtaining ethics committee approval, 60 patients scheduled for bilateral reduction mammaplasty were included in the study. Preoperatively, the patients received one of single (Group S: T3-T4) or double (Group D: T2-T3 & T4-T5) injection bilateral TPVBs using bupivacaine 0.375% 20 ml per side. All patients were operated under general anesthesia. The T3-T6 dermatomal blockade distributions on the midclavicular line were followed by pin-prick test for 30 min preoperatively and 48 h postoperatively. All patients received paracetamol 1 g when numeric rating scale (NRS) pain score was ≥ 4, and also tramadol 1 mg/kg when NRS was ≥ 4 again after 1 h. The primary endpoint was NRS pain scores at postoperative 12th h. The secondary endpoints were dermatomal blockade distributions and NRS scores through the postoperative first 48 h, time until first pain and the analgesic consumption on days 1 and 2.

Results: Fifty-two patients completed the study. The NRS pain scores at 12th h were similar (right side: P = 0.100, left side: P = 0.096). The remaining NRS scores and other parameters were also comparable within the groups (P ≥ 0.05). Only single injection TPVB application time was shorter (P < 0.001).

Conclusions: The single injection TPVB technique provided sufficient dermatomal distribution and analgesic efficacy with the advantages of being faster and less invasive.

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单次和双次注射椎旁阻滞在乳房缩小术中的比较:一项随机对照研究。
背景:本研究比较了单次和双次注射双侧胸椎旁阻滞(TPVB)技术在乳房缩小术患者中的镇痛效果和皮肤阻滞分布。方法:在获得伦理委员会批准后,将60名计划进行双侧乳房缩小术的患者纳入研究。术前,患者接受单次(S组:T3-T4)或双次(D组:T2-T3和T4-T5)注射中的一次双侧TPVBs,每侧使用0.375%20ml布比卡因。所有患者均在全身麻醉下进行手术。术前30分钟和术后48小时对T3-T6型皮块在锁骨中线的分布进行针刺试验。当数值评定量表(NRS)疼痛评分≥4时,所有患者均服用扑热息痛1g,当NRS评分≥4后,1小时后再次服用曲马多1mg/kg。主要终点是术后第12小时的NRS疼痛评分。次要终点是术后首48小时的皮肤阻滞分布和NRS评分,至首次疼痛的时间和第1天和第2天的镇痛药消耗。结果:52名患者完成了研究。第12小时的NRS疼痛评分相似(右侧:P=0.100,左侧:P=0.096)。其余NRS评分和其他参数在组内也具有可比性(P≥0.05)。仅单次注射TPVB的应用时间较短(P<0.001)更快且侵入性更小。
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