[Effect of weight gain on the development of gestational diabetes].

María Guadalupe Suárez-Cruz, Rodolfo Rivas-Ruíz, Dulce Kristel Sarmiento-Galván, Paloma Gabriela Martínez-Valle, Eva Xóchitl Mondragón-Sandoval, Marco Antonio López-Farias, Juan Carlos Rivera-Mendoza, Eduardo Abasolo-Ramírez, Fairt Vladimir Carmona-Sierra
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Abstract

Background: Gestational diabetes mellitus (GDM) refers to diabetes diagnosed in the second or third trimester of pregnancy. Assessing the weight gain in each pregnant women's appointment is a common task of primary care during their visit. However, the implications of this increase in weight for the development of GDM are unknown.

Objective: Evaluate if the greater than expected weight gain (HEWG) in pregnancy is a risk factor for the development of GDM.

Methods: Analytical, observational, longitudinal, retrolective study, which included pregnant women between 15 and 40 years of age with complete follow-up of the preg-nancy with > 2 prenatal check-ups, somatometry and complete medical history was made. During follow-up, the GPME was determined. Odds ratio (OR) and 95% confi-dence intervals (95% CI) were calculated. Variables with significance were entered into a multiple logistic regression model (MLR), where the dependent variable was DMG. The sample size calculation was for convenience.

Results: 1000 pregnant women with a median age of 28 years were included. In the MLR The pre-gestational body mass index (BMI) with overweight had an RM of 1.3 (95% CI 0.86-1.98), BMI with obesity an OR of 2.57 (95% CI 1.6-4.14), the HEWG during pregnancy had an OR 1.14 95% CI (0.71-1.81), Age> 30 years shows an RM of 2.24 (95% CI 1.55-3.25).

Conclusions: HEWG during pregnancy is not an independent risk factor for the devel-opment of GDM. The main ones are age> 30 years and pre-gestational obesity.

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【体重增加对妊娠期糖尿病发展的影响】。
背景:妊娠期糖尿病(GDM)是指在妊娠中期或晚期诊断出的糖尿病。评估每位孕妇预约时的体重增加是她们就诊期间初级保健的一项常见任务。然而,这种体重增加对GDM发展的影响尚不清楚。目的:评估妊娠期大于预期的体重增加(HEWG)是否是GDM发展的危险因素。在随访期间,确定了GPME。计算比值比(OR)和95%置信区间(95%CI)。将具有显著性的变量输入多元逻辑回归模型(MLR),其中因变量为DMG。样本量的计算是为了方便。结果:纳入1000名中位年龄为28岁的孕妇。在MLR中,超重的妊娠前体重指数(BMI)的RM为1.3(95%CI 0.86-1.98),肥胖的BMI的OR为2.57(95%CI 1.6-4.14),妊娠期HEWG的OR为1.14(95%CI 0.71-1.81),年龄>30岁的RM为2.24(95%CI 1.55-3.25)。主要是年龄>30岁和妊娠前肥胖。
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