Utilizing nonlinear behavior of microbubbles in medical ultrasound

Shin-Ichiro Umemura, Ken-Ichi Kawabata, Kazuaki Sasaki
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引用次数: 4

Abstract

Microbubbles exposed to ultrasound exhibit extremely nonlinear conspicuous behaviors. Medical imaging makes wide use of the pulse inversion method, in which only this nonlinear component is extracted by adding the received signals obtained by sending the phase inverted ultrasonic pulses twice. Further, there have been research efforts to use this nonlinear behavior for sonochemical healing of tumors by the efficient generation of acoustic cavitation by illumination with the second harmonic superimposed on the fundamental wave. © 2007 Wiley Periodicals, Inc. Electron Comm Jpn Pt 3, 90(8): 63–69, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecjc.20259

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微气泡的非线性行为在医学超声中的应用
暴露于超声的微气泡表现出极其非线性的显著行为。医学成像广泛使用脉冲反转方法,其中通过将通过发送两次相位反转的超声脉冲而获得的接收信号相加,仅提取该非线性分量。此外,已经有研究努力通过利用叠加在基波上的二次谐波的照射有效地产生声空化,将这种非线性行为用于肿瘤的声化学愈合。©2007 Wiley Periodicals,股份有限公司Electron Comm Jpn Pt 3,90(8):63–691007;在线发表于Wiley InterScience(www.InterScience.Wiley.com)。DOI 10.1002/ecjc.20259
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