Evaluating the Significance of Titanium Clip Marking Under Endoscopy in Upper Gastrointestinal Bleeding Patients with Failed Endoscopic Hemostasis.

IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Alternative therapies in health and medicine Pub Date : 2024-08-01
Jin Zhu, Rongshu Shi, Bangguo Li, Kongwu Yang
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Abstract

Objective: This study investigated the role of titanium clip marking during endoscopy in managing patients with upper gastrointestinal bleeding (UGIB) for whom endoscopic hemostasis has proven ineffective.

Methods: A total of 63 UGIB patients admitted to the Affiliated Hospital of Zunyi Medical University between January 2018 and November 2020 were selected as the study cohort. Patients were randomly assigned to one of two groups: the control group (n=23) and the combined group (n=40). The control group underwent transcatheter arterial embolization (TAE), while the combined group received endoscopic metallic titanium clip-assisted TAE. This study compared the rates of successful embolization, clinical success, recurrence, operation time, radiation exposure time, radiation dosage, levels of hs-CRP, Cor, NE, TNF-α, IL-6, and ADH before and after treatment, as well as postoperative complications between the two groups.

Results: The combined group of patients exhibited significantly higher rates of successful embolization and clinical success compared to the control group (P < .05). Additionally, the recurrence rate and levels of hs-CRP, Cor, NE, TNF-α, IL-6, and ADH were significantly lower in the combined group compared to the control group (P < .05). Furthermore, patients in the combined group had shorter operation times, reduced radiation exposure times, and lower radiation dosages compared to the control group (P < .05). There was no statistically significant difference in the occurrence of postoperative complications between the two groups (P > .05).

Conclusions: Using titanium clip marking during endoscopy provides valuable guidance in managing patients with upper gastrointestinal bleeding who have not responded to endoscopic hemostasis. This finding is especially relevant in digital subtraction angiography (DSA) and transcatheter arterial embolization (TAE) treatments. It enhances the clinical efficacy and safety of the procedure.

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评价内镜下钛夹标记在内镜止血失败的上消化道出血患者中的意义。
目的:本研究探讨内镜下钛夹标记在治疗上消化道出血(UGIB)患者中的作用,这些患者的内镜止血已被证明无效。方法:选择2018年1月至2020年11月期间入住遵义医科大学附属医院的63名UGIB患者作为研究队列。患者被随机分为两组:对照组(n=23)和联合组(n=40)。对照组接受经导管动脉栓塞(TAE),联合组接受内镜下金属钛夹辅助TAE。本研究比较了两组治疗前后栓塞成功率、临床成功率、复发率、手术时间、放疗时间、放疗剂量、hs-CRP、Cor、NE、TNF-α、IL-6和ADH水平以及术后并发症。结果:与对照组相比,联合组患者的栓塞成功率和临床成功率显著较高(P<0.05)。此外,联合组的复发率和hs-CRP、Cor、NE、TNF-α、IL-6和ADH水平显著低于对照组(P<.05),联合组患者的手术时间更短、辐射暴露时间减少,与对照组相比,放射剂量更低(P<0.05)。两组术后并发症的发生率没有统计学上的显著差异(P>0.05)。结论:在内镜下使用钛夹标记为治疗对内镜止血没有反应的上消化道出血患者提供了有价值的指导。这一发现在数字减影血管造影术(DSA)和经导管动脉栓塞(TAE)治疗中尤其重要。它提高了手术的临床疗效和安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Alternative therapies in health and medicine
Alternative therapies in health and medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
0.90
自引率
0.00%
发文量
219
期刊介绍: Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field. Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.
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