Autoimmune Markers in Primary Biliary Cholangitis

IF 2.9 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Clinics in liver disease Pub Date : 2023-08-17 DOI:10.1016/j.cld.2023.07.002
Shivani K. Shah MD, Christopher L. Bowlus MD
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原发性胆管炎的自身免疫标志物。
原发性胆汁性胆管炎(PBC)是一种慢性胆汁淤积性肝病。与PBC相关的最常见的抗体是抗线粒体抗体(AMA),存在于90%至95%的患者中。对于AMA阴性的患者,新的生物标志物,如抗核抗体特异性抗体Sp100和gp210以及抗kelch-like-12和抗己糖激酶-1抗体,可能进一步有助于PBC的诊断。有几种实验室方法,包括免疫荧光、酶联免疫吸附测定、免疫印迹和基于珠的测定,用于评估抗体的存在。本文介绍了用于评估抗体的各种方法,以及PBC中存在的抗体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinics in liver disease
Clinics in liver disease GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.30
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: A perfect source to consult for those in the fields of gastroenterology and hepatology, Clinics in Liver Disease provides answers to clinical questions, information on the latest diagnostic methods and treatments, and numerous clinical images. Published quarterly—in February, May, August, and November—each issue offers in-depth reviews that focus on the liver and biliary system.
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Contents Alcohol-Associated Liver Disease: Treatment and Prevention Treatment of Alcohol Use Disorder Alcohol-Associated Liver Disease Copyright
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