Treatment of Primary Sclerosing Cholangitis Including Transplantation

IF 2.9 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Clinics in liver disease Pub Date : 2023-08-17 DOI:10.1016/j.cld.2023.07.008
William H. Wheless MD, Mark W. Russo MD, MPH
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原发性硬化性胆管炎的治疗包括移植。
原发性硬化性胆管炎是一种进行性胆汁淤积性肝病,可导致肝内外胆管狭窄,从而导致肝硬化和终末期肝病。有效的药物治疗一直难以捉摸,但可以开出一个疗程的熊去氧胆酸,剂量为17-23 mg/kg/天,持续长达一年,以确定是否观察到血清碱性磷酸酶降低。许多药物正在研究中,包括具有利胆和抗菌特性的FXR激动剂。肝移植治疗PSC的存活率最高,但高达25%的受试者出现复发性PSC。
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来源期刊
Clinics in liver disease
Clinics in liver disease GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.30
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: A perfect source to consult for those in the fields of gastroenterology and hepatology, Clinics in Liver Disease provides answers to clinical questions, information on the latest diagnostic methods and treatments, and numerous clinical images. Published quarterly—in February, May, August, and November—each issue offers in-depth reviews that focus on the liver and biliary system.
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Contents Alcohol-Associated Liver Disease: Treatment and Prevention Treatment of Alcohol Use Disorder Alcohol-Associated Liver Disease Copyright
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