Electroconvulsive therapy for obsessive compulsive symptoms in a patient with schizophrenia: a brief report.

IF 0.6 4区 医学 Q4 CLINICAL NEUROLOGY Neurocase Pub Date : 2023-02-01 Epub Date: 2023-12-16 DOI:10.1080/13554794.2023.2280274
Chih-Yuan Lin, Hsin-Ya Kuo, Cheng-Ho Chang, Chih-Chuan Pan, Che-Sheng Chu, Jeremy Couper, Yung-Chih Chiang
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Abstract

Comorbid obsessive-compulsive disorder (OCD) is common among patients with schizophrenia. The role of electroconvulsive therapy (ECT) in the treatment of OCD in schizophrenia is unclear. Herein, we present a 45-year-old man who was diagnosed with schizophrenia along with OCD and received ECT due to relapse of psychosis owing to refractive schizophrenia. Together with psychotic symptoms, obvious symptoms of OCD were observed prior to treatment, including obsessive thoughts, difficulty in starting activities, and repetitive and ritualistic behavior. After 12 sessions of ECT, symptoms of schizophrenia and OCD both improved significantly (Positive and Negative Syndrome Scale [PANSS] score decreased from 95 points to 58 points, and Yale - Brown Obsessive-Compulsive Scale [Y-BOCS] score decreased from 29 points to 11 points). Mild aggravation of OCD symptoms was noted 3 months after ECT treatment (Y-BOCS score increased from 11 points to 17 points) without obvious relapse of psychotic symptoms (PANSS score changed from 58 points to 62 points). In conclusion, ECT could be considered as an alternative therapy for patients with schizophrenia and OCD with limited response to pharmacological treatment.

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精神分裂症患者强迫症状的电休克治疗:一份简短报告。
合并强迫症(OCD)在精神分裂症患者中很常见。电休克疗法(ECT)在精神分裂症强迫症治疗中的作用尚不清楚。在此,我们介绍一名45岁的男性,他被诊断为精神分裂症伴强迫症,并因屈光性精神分裂症导致精神病复发而接受ECT治疗。除了精神病症状外,在治疗前还观察到明显的强迫症症状,包括强迫性思维、难以开始活动以及重复和仪式性行为。ECT治疗12次后,精神分裂症和强迫症症状均明显改善(阳性和阴性综合征量表[PASS]评分从95分降至58分,Yale-Brown强迫症量表[Y-BOCS]评分从29分降至11分)。强迫症症状轻度加重3 ECT治疗后数月(Y-BOCS评分从11分增加到17分),没有明显的精神病症状复发(PANSS评分从58分增加到62分)。总之,ECT可以被视为对药物治疗反应有限的精神分裂症和强迫症患者的替代疗法。
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来源期刊
Neurocase
Neurocase 医学-精神病学
CiteScore
1.40
自引率
12.50%
发文量
70
审稿时长
6-12 weeks
期刊介绍: Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.
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