{"title":"Kétolides","authors":"N. Viget , L. Legout , S. Alfandari","doi":"10.1016/j.emcmi.2004.09.001","DOIUrl":null,"url":null,"abstract":"<div><p>Ketolides are semi-synthetic derivatives of Erythromycin A. Telithromycin is the first introduced in clinical practice. It was developed specifically for the treatment of community-acquired respiratory tract infections, since it demonstrates bacteriological efficiency against common and atypical respiratory pathogens, as well as good diffusion in respiratory tissues. It maintains efficacy against erythromycin resistant Gram-positive cocci and seems to not induce MLS<sub>B</sub> resistance. Telithromycin is available currently, but the other agents of this therapeutic class are not marketed yet.</p></div>","PeriodicalId":100430,"journal":{"name":"EMC - Maladies Infectieuses","volume":"2 1","pages":"Pages 33-41"},"PeriodicalIF":0.0000,"publicationDate":"2005-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcmi.2004.09.001","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"EMC - Maladies Infectieuses","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1638623X04000228","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Ketolides are semi-synthetic derivatives of Erythromycin A. Telithromycin is the first introduced in clinical practice. It was developed specifically for the treatment of community-acquired respiratory tract infections, since it demonstrates bacteriological efficiency against common and atypical respiratory pathogens, as well as good diffusion in respiratory tissues. It maintains efficacy against erythromycin resistant Gram-positive cocci and seems to not induce MLSB resistance. Telithromycin is available currently, but the other agents of this therapeutic class are not marketed yet.
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