Secretory Immunoglobulin A and Upper Cervical Chiropractic: A Preliminary Prospective, Multicenter, Observational Study

Journal of chiropractic medicine Pub Date : 2021-09-01 DOI:10.1016/j.jcm.2021.10.003

Philip R. Schalow DC, DCCJP , Kelly A. Kimball DC , Frederick T. Schurger DC, DCCJP , George R. Sooley DC, DCCJP , Scott P. Bales DC, DCCJP , Roderic P. Rochester DC, FCCJP , Robert T. Brooks DC , Julie M. Hunt DC, FCCJP, DICCP

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Abstract

Objective

The objective of this study was to observe changes in secretory immunoglobulin A (SIgA) after chiropractic care using upper cervical adjusting techniques (UCATs) at the craniocervical junction (CCJ).

Methods

Forty-one participants were enrolled from 5 chiropractic offices in North America. Each participant provided a saliva sample at an initial visit before care. A second saliva sample was collected after resting 30 minutes after the first UCAT treatment. A third saliva sample was collected after 2 weeks.

Results

There was a significant increase in SIgA observed 30 minutes after the UCAT treatment compared to baseline. After 2 weeks, SIgA levels decreased back to near original levels.

Conclusion

Our preliminary findings demonstrate an immediate, temporary increase in SIgA levels after a UCAT treatment at the CCJ.

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分泌性免疫球蛋白A与上颈椎脊医：一项前瞻性、多中心、观察性的初步研究

目的本研究旨在观察应用上颈椎调节技术（UCAT）在颅颈交界处（CCJ）进行脊骨神经医学治疗后分泌型免疫球蛋白A（SIgA）的变化。每位参与者在护理前的初次就诊时提供了唾液样本。在第一次UCAT处理后静置30分钟后收集第二唾液样本。2周后采集第三份唾液样本。结果与基线相比，UCAT治疗后30分钟观察到的SIgA显著增加。2周后，SIgA水平下降至接近原始水平。结论我们的初步发现表明，在CCJ接受UCAT治疗后，SIgA水平立即、暂时升高。

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来源期刊

Journal of chiropractic medicine

CiteScore

1.50

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0.00%

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