A Simple Mathematical Model for Wound Closure Evaluation

The journal of the American College of Clinical Wound Specialists Pub Date : 2015-12-01 DOI:10.1016/j.jccw.2016.07.002

Alejandra Vidal MD , Hugo Mendieta Zerón PhD , Israel Giacaman , María del Socorro Camarillo Romero PhD , Sandra Parra López , Laura E. Meza Trillo MD , David A. Pérez Pérez , Miguel Concha PhD , César Torres-Gallegos , Sandra L. Orellana PhD , Felipe Oyarzun-Ampuero PhD , Ignacio Moreno-Villoslada PhD

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引用次数: 9

Abstract

The incidence of ulcers associated to type 2 diabetes mellitus (T2DM) increases every year. We introduce and explore a new mathematical algorithm to evaluate wound-healing in foot ulcers associated to T2DM. Fifteen patients (nine women and six men), mean age of 70 ± 16 years were included. The evolution of their wounds followed-up for a period of 18–45 days. According to the Wagner grading system the ulcers were grade I (5 patients), grade II (9 patients), and grade III (1 patient). Clinically, the type of the ulcers was neuroischemic (12 patients) and neuropathic (3 patients). A new parameter is introduced, the “continuous linear healing rate” Dc that was more accurate with higher values and requires less quantifications than usual formulas to make a wound-healing projection.

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伤口闭合性评价的一个简单数学模型

与2型糖尿病（T2DM）相关的溃疡的发病率每年都在增加。我们介绍并探索了一种新的数学算法来评估T2DM相关足部溃疡的伤口愈合情况。包括15名患者（9名女性和6名男性），平均年龄70±16岁。他们伤口的演变持续了18-45天。根据Wagner分级系统，溃疡为I级（5名患者）、II级（9名患者）和III级（1名患者）。临床上，溃疡类型为神经缺血性溃疡（12例）和神经性溃疡（3例）。引入了一个新的参数，“连续线性愈合率”Dc，该参数比通常的公式更准确，具有更高的值，并且需要更少的量化来进行伤口愈合预测。

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The journal of the American College of Clinical Wound Specialists

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