¿Qué variables se asocian con un buen control metabólico en pacientes con diabetes tipo 1?

Florentino Carral San Laureano , José Vicente Gutiérrez Manzanedo , Carmen Ayala Ortega , Manuel Aguilar Diosdado
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引用次数: 1

Abstract

Objectives

To evaluate the epidemiological, clinical and healthy lifestyle adherence variables that are associated with HbA1c  7% in patients with type 1 diabetes (DM-1).

Methods

A descriptive observational study was conducted in 130 patients with DM-1 of 33.7 ± 11.7 years old. Various clinical, anthropometric and analytical variables were analysed, together with the results of the “Minnesota Leisure Time Physical Activity Questionnaire” and “Adherence to the Mediterranean Diet Questionnaire”.

Results

Patients with HbA1c  7% (n = 39) spent more time on physical activity (PA) (999.7 ± 538.6 versus 719.5 ± 386.0 versus 834.2 ± 512.7 minutes/PA/week, P = .010) and intense PA (180.6 ± 80.4 versus 259.3 ± 125.5 versus 104.3 ± 139.9 minutes/PA intense/week, P = .037), compared with patients with HbA1c between 7-8% (n = 41) and higher than 8% (n = 50). Patients with HbA1c  7% were more likely to be college graduates (77%) than patients of other groups. There were no significant differences in HbA1c levels according to age, sex, diabetes evolution, body mass index, number of hypoglycaemia, presence of chronic complications, or adherence to the Mediterranean diet. In the multivariate analysis, the independent variables “college graduate” and “spent more than 150 minutes of intense physical activity a week” showed a significant association with the dependent variable “HbA1c  7%”.

Conclusions

In our study, patients with DM-1 and HbA1c  7% were most often college graduates and spent more time practicing intense physical activity than patients with poor metabolic control.

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哪些变量与1型糖尿病患者良好的代谢控制有关?
目的评价1型糖尿病(DM-1)患者HbA1c≤7%的流行病学、临床和健康生活方式依从性变量。方法对130例年龄为33.7±11.7岁的DM-1患者进行描述性观察研究。分析了各种临床、人体测量和分析变量,结果HbA1c≤7%(n=39)的患者在体育活动(PA)(999.7±538.6对719.5±386.0对834.2±512.7分钟/PA/周,P=0.010)和剧烈PA上花费的时间较多(180.6±80.4对259.3±125.5对104.3±139.9分钟/PA强度/周,P=0.037),而HbA1c在7-8%(n=41)和高于8%(n=50)之间的患者。HbA1c≤7%的患者更有可能是大学毕业生(77%),而不是其他组的患者。HbA1c水平在年龄、性别、糖尿病演变、体重指数、低血糖次数、是否存在慢性并发症或是否坚持地中海饮食方面没有显著差异。在多变量分析中,自变量“大学毕业生”和“每周进行150分钟以上的剧烈体育活动”与因变量“HbA1c≤7%”存在显著相关性,DM-1和HbA1c≤7%的患者通常是大学毕业生,与代谢控制不佳的患者相比,他们花更多的时间进行剧烈的体育活动。
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