Impact of Obesity on the Pathogenesis and Prognosis of Coronary Heart Disease

M. Todd Miller MD, Carl J. Lavie MD, Christopher J. White MD
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引用次数: 48

Abstract

Obesity has a significant adverse effect on coronary heart disease (CHD) risk factors, including hypertension, dyslipidemia, and the metabolic syndrome/diabetes. Obesity is an independent risk factor for CHD events; however, obese patients with CHD generally have a more favorable prognosis, with the worst prognosis associated with either underweight or morbidly obese patients. In this manuscript, the authors review the impact of obesity on overall CHD risk as well as the prognosis of obese patients with established CHD.

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肥胖对冠心病发病机制和预后的影响
肥胖对冠心病的危险因素有显著的不良影响,包括高血压、血脂异常和代谢综合征/糖尿病。肥胖是冠心病事件的独立危险因素;然而,肥胖的CHD患者通常有更有利的预后,最差的预后与体重不足或病态肥胖患者有关。在这篇文章中,作者综述了肥胖对冠心病总风险的影响,以及肥胖合并冠心病患者的预后。
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