Ultrasound Ablation and Autologous Transplantation of Bone Marrow Mononuclear Cells for Treating Elderly Patients with Arteriosclerosis Obliterans

Abstract

Objective To investigate the efficacy of ultrasound ablation and autologous transplantation of bone marrow mononuclear cells in treatment of elderly patients with arteriosclerosis obliterans.Methods 22 patients with arteriosclerosis obliterans were treated with ultrasound ablation and autologous transplantation of bone marrow mononuclear cells.Through percutaneous approach or surgical approach the ultrasound ablation catheter was inserted into occluded arterial segments.After ablation performed,autologous bone marrow mononuclear cells were directly injected into the skeletal muscles of the ischemic crura.Results No complications were found in this group.Postopertaively rest pain of all the patients got significient improvement.The skin turned warm in all legs.Conclusion Ultrasound ablation and autologous transplantation of bone marrow mononuclear cells could be simple,safe and effective method for treating patients with diabetic feet.Although its long term effect need to follow up and in more patients,an alternative choice to treat these patients is found expect amputation.