Design of a Highly Sensitive Detector Using a Ternary Photonic Crystal (PC) Based on Titanium Nitride Sandwiched between Si and SiO2 for the Creatinine Concentration Detection in the Blood Serum

3区 物理与天体物理 Q1 Materials Science Progress in Optics Pub Date : 2022-11-29 DOI:10.3390/opt3040038
Malek G. Daher, Y. Trabelsi, A. Panda, A. Gevorgyan, Khedr M. Abohassan, Lassaad K. Smirani, Baraa Riyadh Altahan, A. Rashed
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引用次数: 8

Abstract

It is very important to design a rapid and sensitive device for the creatinine concentration detection due to it being one of the most considerable benchmarks for efficient kidney working. Here, a novel biophotonic sensor using one-dimensional ternary PC based on Si/TiN/SiO2 layers is proposed for the creatinine concentration detection in a blood serum sample. A central cavity layer is inserted between two equal periodic numbers. The blood sample can be infiltrated in the cavity layer with various creatinine concentrations. Based on the technique of transfer matrix, the transmittance spectra properties are investigated. The influences of variation of the incidence angle for both TE and TM polarizations and the cavity layer thickness are carefully investigated to attain the best sensitivity of the biophotonic detector. A high sensitivity of 938.02 nm/RIU is realized for the suggested detector, which is comparable to most recent works published in this area. Moreover, the proposed sensor has an inexpensive cost, real-time detection, and simple structure, which is helpful to the industrial design using low-cost product nanofabrication techniques. Based on above-mentioned outcomes, our biosensor candidate is a suitable and effective device for the detection of creatinine concentration, and it can use for any biological sample.
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基于Si和SiO2夹层氮化钛三元光子晶体(PC)的高灵敏度血清肌酐检测仪的设计
设计一种快速、灵敏的肌酐浓度检测装置是肾脏工作效率的重要指标之一。本文提出了一种基于Si/TiN/SiO2层的一维三元PC生物光子传感器,用于血清肌酐浓度检测。在两个相等的周期数之间插入一个中心腔层。不同浓度的肌酐可使血液样本浸润于腔层。基于传递矩阵技术,对其透射光谱特性进行了研究。研究了入射角度的变化对TE和TM极化以及腔层厚度的影响,以获得生物光子探测器的最佳灵敏度。该探测器的灵敏度可达938.02 nm/RIU,与该领域的最新研究成果相当。此外,该传感器具有成本低廉、检测实时、结构简单等优点,有助于采用低成本的产品纳米加工技术进行工业设计。基于上述结果,我们的候选生物传感器是一种适合和有效的检测肌酐浓度的设备,它可以用于任何生物样品。
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来源期刊
Progress in Optics
Progress in Optics 物理-光学
CiteScore
4.50
自引率
0.00%
发文量
8
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