PREPARATION AND EVALUATION OF PANCHA HARITHAKADI CHURNA FOR DIGESTIVE ACTIVITY

S. Sarala, D. Chamundeeswari, V. Gopal
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Abstract

Pancha Harithakadi Churna (PHC) is a traditional polyherbal formulation meant for digestion which consists of household ingredients having digestive property. PHC is mainly used for Constipation and Bloating. Churna’s will play an important role in gastro intestinal problems. Churna’s are having greater bioavailability because of smaller particle size. It consists of fine powder (sieve 100 size) of Ginger rhizomes, Fennel fruits, Myrobalan fruits, Senna leaflets and Pink Rock salt in equal proportions (1:1:1:1:1) are mixed well. PHC is formulated by standard procedures and evaluated by physical and analytical methods. Physicochemical standards and heavy metals are found to be within the limits. PHC is found to be free from microbes. The PHC showed pronounced amylolytic activity and moderate lipolytic and proteolytic activity when compared with standard showing its efficacy for treating indigestion. In future we will carry out other digestive enzymes in vitro studies and also to carry out in vivo digestive studies.
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肉苁蓉的制备及消化活性评价
Pancha Harithakadi Churna (PHC)是一种传统的多草药配方,用于消化,由具有消化特性的家庭成分组成。PHC主要用于便秘和腹胀。Churna 's将在胃肠道问题中发挥重要作用。由于颗粒尺寸更小,Churna具有更高的生物利用度。它由姜根茎、茴香果、八哥果、番泻小叶和粉岩盐按等比例(1:1:1:1:1)混合而成(筛子100大小)。PHC由标准程序制定,并通过物理和分析方法进行评估。理化标准和重金属含量均在限定范围内。PHC被发现没有微生物。与标准品相比,PHC具有明显的解淀粉活性和中等的解脂和解蛋白活性,显示其治疗消化不良的疗效。在未来,我们将进行其他消化酶的体外研究,也将进行体内消化研究。
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