Two Clinical Cases of Secondary Neoplasia After Remission of Hodgkin’s Disease

V. S. Popova
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Abstract

Summary Hodgkin’s disease is one of the most common lymphomas in young people. In such cases, long-lasting hematological remissions are achievable using therapeutic regimens, including combined radiotherapy and chemotherapy. This publication aims to present clinical cases from our practice in patients with Hodgkin’s disease in whom the occurrence of second neoplasia is probably causally related to the treatment of Hodgkin’s lymphoma. We present two clinical cases of women with established secondary neoplasia (breast carcinoma, diffuse large B cell lymphoma) 20 years after treatment for Hodgkin’s disease had been completed. The probability of developing another neoplastic disease, leading to increased mortality in these patients, requires updating the recommendations for secondary prevention in oncology.
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何杰金氏病缓解后继发肿瘤2例临床分析
何杰金氏病是年轻人中最常见的淋巴瘤之一。在这种情况下,使用治疗方案,包括联合放疗和化疗,可以实现长期的血液学缓解。本出版物旨在介绍我们在霍奇金淋巴瘤患者的临床病例,其中第二次肿瘤的发生可能与霍奇金淋巴瘤的治疗有因果关系。我们报告了两例女性在霍奇金淋巴瘤治疗完成20年后继发性肿瘤(乳腺癌,弥漫性大B细胞淋巴瘤)的临床病例。发生另一种肿瘤疾病的可能性,导致这些患者死亡率增加,需要更新肿瘤二级预防的建议。
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