{"title":"A Precipitant Less Appreciated: A Glance at Cases of Tuberculosis Manifesting with Guillain Barre Syndrome","authors":"Camelia Porey, B. Jaiswal","doi":"10.1177/26339447221145821","DOIUrl":null,"url":null,"abstract":"Guillain-Barre syndrome (GBS) is an immune triggered inflammatory polyneuropathy precipitated by various triggers by means of cross reactivity and molecular mimicry. Tuberculosis (TB) of any organ, although may produce features of peripheral neuropathy, has rarely been associated with GBS. We describe a middle-aged female patient in whom pulmonary TB manifested with GBS primarily without any prominent constitutional symptoms and review the literature to strengthen our viewpoint in this regard. The treatment with immunomodulators is beneficial with good outcome and thus early diagnosis and intervention is suggested.","PeriodicalId":40062,"journal":{"name":"Journal, Indian Academy of Clinical Medicine","volume":"66 1","pages":"43 - 52"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal, Indian Academy of Clinical Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/26339447221145821","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Guillain-Barre syndrome (GBS) is an immune triggered inflammatory polyneuropathy precipitated by various triggers by means of cross reactivity and molecular mimicry. Tuberculosis (TB) of any organ, although may produce features of peripheral neuropathy, has rarely been associated with GBS. We describe a middle-aged female patient in whom pulmonary TB manifested with GBS primarily without any prominent constitutional symptoms and review the literature to strengthen our viewpoint in this regard. The treatment with immunomodulators is beneficial with good outcome and thus early diagnosis and intervention is suggested.
期刊介绍：
Indian Association of Clinical Medicine is an academic body constituted in the year 1992 by a group of clinicians with the main aim of reaffirming the importance of clinical medicine in this era of high-tech diagnostic modalities. There is no doubt that modern investigational methods have contributed a lot to the present day medical practice but that does not render clinical acumen and examination less important. The art and science of clinical medicine helps up to make proper and judicious use of investigations and not these be the sole basis of our practice. That is the basic idea behind this ''Association''. We presently have members and fellows of the association from all over the country. In August, 2002 the body was registered as "Indian Association of Clinical Medicine" by the Registrar of Societies, Delhi.
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