Persistent Diuresis Associated Dapagliflozin Treatment

Abstract

Diabetic ketoacidosis is a clinical entity characterized by high blood sugar, ketone positivity and high anion gap metabolic acidosis. In these patients; polyuria is commonly detected due to hyperglycemia. Polyuria-induced dehydration may even be seen, especially in elderly patients. Polyuria is not expected to continue after hyperglycemia has resolved. We reported in this article; a 55 years old man with type-2 diabetes mellitus who was treated with a sodium-glucose cotransporter 2 (SGLT2) inhibitor (dapagliflozin) who developed diabetic ketoacidosis and persistent diuresis in the post-treatment normoglycemic period.