The protective effect of gallic acid on tartrazine-induced renotoxicity: Redox potential and morphological study

H. Waly, Rahma Ez Al-arab, Shaimaa M. M. Saleh, Mohamed El-salahy, M. Saleh
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Abstract

Tartrazine (Tz) is a commonly used artificial food dye which adversely impacts the health status. A broad spectrum of literatures indicates that gallic acid (GA) exert antioxidant and cytoprotective effects. Therefore, this study aimed to estimate the effect of four fold permitted dose of Tz as well as protective effects of GA on Tz-induced renotoxicity in adult male Wistar rats. Tz was administered daily at a dose of 30 mg/kg body weight alone orally, in combination with GA
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没食子酸对酒石黄致肾毒性的保护作用:氧化还原电位和形态学研究
酒黄石(Tz)是一种常用的人工食用色素,对人体健康有不良影响。广泛的文献表明没食子酸(GA)具有抗氧化和细胞保护作用。因此,本研究旨在评估四倍允许剂量的Tz对成年雄性Wistar大鼠的影响以及GA对Tz诱导的肾毒性的保护作用。Tz每日单独口服剂量为30mg /kg体重,与GA联合使用
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