Zolmitriptan and the Triptan Era

M. Marmura
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引用次数: 0

Abstract

Zolmitriptan is one of seven triptans available to treat acute migraine attacks. The introduction of these selective serotonin receptor agonists almost 20 years ago has revolutionized acute migraine treatment. Triptans are now first line migraine drugs, and provide acute treatment that is well-tolerated, safe and effective. This commentary reviews the use of zolmitriptan and other triptans, discusses how to maximize their effect, and examines the controversies surrounding this class of medication such as medication-overuse headache, use in migraine aura or prodrome, pediatric use, and important drug interactions.
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曲曲坦和曲曲坦时代
佐米曲坦是治疗急性偏头痛发作的七种曲坦类药物之一。大约20年前,这些选择性血清素受体激动剂的引入彻底改变了急性偏头痛的治疗。曲坦类药物现在是一线偏头痛药物,提供耐受性良好、安全有效的急性治疗。这篇评论回顾了唑米曲坦和其他曲坦类药物的使用,讨论了如何最大化其效果,并检查了围绕这类药物的争议,如药物过度使用头痛,用于偏头痛先兆或前驱症状,儿科使用,以及重要的药物相互作用。
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