Clinico-epidemiological Study on Self-induced Poisoning Caused by Substances Other than Organophosphorus Compound

I. Ara, Rabiul Alam Md Erfan Uddin, A. Ghose
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Abstract

Background: Though Organophosphorus Compounds (OPC) are mostly used for self-induced poisoning, non- OPC poisoning cases are increasing day by day. This study was done to describe clinical pattern and outcome of poisoning other than OPC.  Materials and methods: This observational study was conducted in the Medicine Ward of Chittagong Medical College Hospital. Data were collected in structured case record forms. Total 204 patients (n=204) were included in the study after fulfilling the inclusion criteria. Data were analyzed with SPSS and expressed as percentage, mean with standard deviation as appropriate. Results: Out of 204 patients, most were female (60.8%). Most of the patients were young, 56.9% patients were unmarried, 60.8% poisoned patients resided in metropolitan area, most were with low educational level, 57.4% patients came from the middle class socioeconomic group, 82.4% patients were poisoned by a single agent and 17.6% by multiple agents. Offending agents were identified in 96.6% cases. Poisoning by drugs was the highest (47.1%) followed by rat killer poisoning (22.5%) poisoning by non-OPC insecticides (6.9%) corrosive poisoning (6.4%) chemical poisoning (3.9%) and alcohol poisoning (1%). Family disharmony was the underlying cause of self-harm in 47.1% cases, financial constraints in 8.3%, social crisis in 7.8%, failure in love affairs in 6.4% and academic failure in 2.5% patients. 14.7% patients poisoned themselves to gain some benefit by the act of self-harm. 81.4% patients were discharged with advice, 2.9% died. Conclusion: Burden of Non-OPC poisoning is high. Outcome is not so fatal as OPC, but the problem has to be addressed in large scale. JCMCTA 2021 ; 32 (2) : 34-40
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非有机磷化合物所致自致中毒的临床流行病学研究
背景:有机磷化合物(OPC)中毒多用于自致中毒,但非OPC中毒病例日益增多。本研究是为了描述除OPC以外的中毒的临床模式和结果。材料与方法:本观察性研究在吉大港医学院附属医院内科病房进行。数据以结构化的病例记录表格收集。在满足纳入标准后,共纳入204例患者(n=204)。数据采用SPSS统计软件进行分析,以百分比表示,取平均值,标准差适当。结果:204例患者中,女性居多(60.8%)。患者以年轻人居多,未婚占56.9%,60.8%的患者居住在大城市,文化程度较低,57.4%的患者来自中产阶级社会经济群体,82.4%的患者为单一药物中毒,17.6%的患者为多种药物中毒。96.6%的病例中发现了违规物质。药物中毒最多(47.1%),其次是灭鼠剂中毒(22.5%)、非opc类杀虫剂中毒(6.9%)、腐蚀性中毒(6.4%)、化学中毒(3.9%)和酒精中毒(1%)。家庭不和谐是自残的根本原因,占47.1%,经济拮据占8.3%,社会危机占7.8%,恋爱失败占6.4%,学业失败占2.5%。14.7%的患者通过自残行为毒害自己以获得某种利益。81.4%的患者按建议出院,2.9%的患者死亡。结论:非opc中毒负担高。结果不像OPC那样致命,但问题必须大规模解决。Jcmcta 2021;32 (2): 34-40
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