{"title":"Clinical effects of 23-gauge micro-invasive vitrectomy combined with triamcinolone acetonide on the treatment for proliferative diabetic retinopathy","authors":"Lin Zhou","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.10.008","DOIUrl":null,"url":null,"abstract":"Objective \nTo study the safety and efficacy of 23-gauge micro-invasive vitrectomy combined with posterior sub-Tenoncapsule injection of triamcinolone acetonide (PSTA) in treating proliferative diabetic retinopathy (PDR). \n \n \nMethods \nThe clinical data of 46 patients with PDR (48 eyes) from June 2014 to June 2016 in Department of Ophthalmology, Huaian Hospital of Xuzhou Medical College were retrospectively analyzed. Pars plana vitrectomy combined with triamcinolone acetonide (TA) was performed on 48 eyes suffered from proliferative diabetic retinopathy and 8 mg of TA was injected into the eyes for dying of vitreous during the operations and 30mg of TA was injected in the posterior sub-Tenon capsule. Postoperatively, the best corrected visual acuity (BCVA), intraocular pressure (IOP), changes of macular central fovea thickness, intraoperative and postoperative complications were observed. \n \n \nResults \nThe BCVA was improved in 36 eyes (75%) after 3mo and 28 eyes (58.33%) after 6mo, there was statistical difference with preoperative (P 0.05). Macula central fovea thickness was 296.05±51.71, 277.15±41.24, 254.83±33.62, and 226.47±28.56um at 7d, 1, 3 and 6mo respectively. The differences had statistically significant at 7d, 1, 3 and 6mo compared with preoperative 433.52±101.03um (P <0.05). Intraoperative complications: 5 eyes (10.42%) happened latrogenic tear hole, 11 eyes (22.92%8%) happened retinal hemorrhage; Postoperative complications: 8 eyes (16.67%) found hyphema, 7 eyes (14.58%) presented fundus hemorrhage. \n \n \nConclusions \n23-gauge micro-invasive vitrectomy combined with posterior sub-Tenon capsule injection of triamcinolone acetonide in treating proliferative diabetic retinopathy is safe and effective, and the patients can reduce macular edema and improve visual acuity. \n \n \nKey words: \n23-gauge micro-invasive vitrectomy; Proliferative diabetic retinopathy; Triamcinolone acetonide (TA); Dying of vitreous; Posterior sub-Tenon capsule injection","PeriodicalId":10236,"journal":{"name":"中国实用眼科杂志","volume":"24 1","pages":"974-979"},"PeriodicalIF":0.0000,"publicationDate":"2017-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国实用眼科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.10.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To study the safety and efficacy of 23-gauge micro-invasive vitrectomy combined with posterior sub-Tenoncapsule injection of triamcinolone acetonide (PSTA) in treating proliferative diabetic retinopathy (PDR).
Methods
The clinical data of 46 patients with PDR (48 eyes) from June 2014 to June 2016 in Department of Ophthalmology, Huaian Hospital of Xuzhou Medical College were retrospectively analyzed. Pars plana vitrectomy combined with triamcinolone acetonide (TA) was performed on 48 eyes suffered from proliferative diabetic retinopathy and 8 mg of TA was injected into the eyes for dying of vitreous during the operations and 30mg of TA was injected in the posterior sub-Tenon capsule. Postoperatively, the best corrected visual acuity (BCVA), intraocular pressure (IOP), changes of macular central fovea thickness, intraoperative and postoperative complications were observed.
Results
The BCVA was improved in 36 eyes (75%) after 3mo and 28 eyes (58.33%) after 6mo, there was statistical difference with preoperative (P 0.05). Macula central fovea thickness was 296.05±51.71, 277.15±41.24, 254.83±33.62, and 226.47±28.56um at 7d, 1, 3 and 6mo respectively. The differences had statistically significant at 7d, 1, 3 and 6mo compared with preoperative 433.52±101.03um (P <0.05). Intraoperative complications: 5 eyes (10.42%) happened latrogenic tear hole, 11 eyes (22.92%8%) happened retinal hemorrhage; Postoperative complications: 8 eyes (16.67%) found hyphema, 7 eyes (14.58%) presented fundus hemorrhage.
Conclusions
23-gauge micro-invasive vitrectomy combined with posterior sub-Tenon capsule injection of triamcinolone acetonide in treating proliferative diabetic retinopathy is safe and effective, and the patients can reduce macular edema and improve visual acuity.
Key words:
23-gauge micro-invasive vitrectomy; Proliferative diabetic retinopathy; Triamcinolone acetonide (TA); Dying of vitreous; Posterior sub-Tenon capsule injection
期刊介绍：
China Practical Ophthalmology was founded in May 1983. It is supervised by the National Health Commission of the People's Republic of China, sponsored by the Chinese Medical Association and China Medical University, and publicly distributed at home and abroad. It is a national-level excellent core academic journal of comprehensive ophthalmology and a series of journals of the Chinese Medical Association.
China Practical Ophthalmology aims to guide and improve the theoretical level and actual clinical diagnosis and treatment ability of frontline ophthalmologists in my country. It is characterized by close integration with clinical practice, and timely publishes academic articles and scientific research results with high practical value to clinicians, so that readers can understand and use them, improve the theoretical level and diagnosis and treatment ability of ophthalmologists, help and support their innovative development, and is deeply welcomed and loved by ophthalmologists and readers.
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