Association of Age with the Expression of Denervation Marker in the Neuromuscular Junction of Male Wistar Rats

Z. Geramian, M. Kordi, F. Shabkhiz, S. B. Jameie
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Abstract

Methods: In this study, 7 young adult male rats of 4 to 6 months of age and 7 old male rats of 24 to 26 months of age, were tested. after a twoweek familiarization period, the soleus and plantaris muscles of the rats were removed, embedded, and subjected to immunohistochemically staining to determine the neuromuscular junction site and neural cell adhesion molecule (NCAM) expression rate. The results were analyzed by analysis of variance at the significant level of p ≤ 0.01.
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年龄与雄性Wistar大鼠神经肌肉连接处去神经支配标志物表达的关系
方法:选取7只4 ~ 6月龄的年轻成年雄性大鼠和7只24 ~ 26月龄的老年雄性大鼠进行实验。2周熟悉期后,取大鼠比目鱼肌和足底肌,包埋,免疫组织化学染色,测定神经肌肉连接部位和神经细胞粘附分子(NCAM)表达率。采用方差分析,p≤0.01为显著水平。
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