{"title":"Chronic venous disorders: from macrocirculation to microcirculation","authors":"P. Antignani","doi":"10.24019/JTAVR.49","DOIUrl":null,"url":null,"abstract":"Recent findings suggest that inflammatory processes are involved in the structural remodelling in venous valves and in the vein wall, leading to valve incompetence and the development of varicose veins. This has been shown by several authors who found infiltration of valve leaflets and the venous wall by leukocytes (monocytes and tissue macrophages) in all valve specimens from patients with chronic venous disease (CVD) and in none from controls.","PeriodicalId":17406,"journal":{"name":"Journal of Theoretical and Applied Vascular Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Theoretical and Applied Vascular Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24019/JTAVR.49","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Recent findings suggest that inflammatory processes are involved in the structural remodelling in venous valves and in the vein wall, leading to valve incompetence and the development of varicose veins. This has been shown by several authors who found infiltration of valve leaflets and the venous wall by leukocytes (monocytes and tissue macrophages) in all valve specimens from patients with chronic venous disease (CVD) and in none from controls.