A ‘real‐world’ retrospective multi‐centre cohort study comparing infliximab and adalimumab for the maintenance of remission in ulcerative colitis

GastroHep Pub Date : 2021-06-02 DOI:10.1002/ygh2.467
V. Kronsten, M. Colwill, S. Nayeemuddin, J. Limdi, C. Selinger, G. Scott, L. Al‐Hillawi, S. Salehi, P. Blaker, G. Chung-Faye, A. Kent, P. Dubois, B. Hayee
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引用次数: 1

Abstract

Anti‐tumour necrosis factor therapy is an established treatment for moderate‐to‐severely active ulcerative colitis (UC). Recent network meta‐analyses of controlled trial data have indicated a superiority of intravenous drugs (infliximab) over subcutaneous (adalimumab). We conducted a retrospective multi‐centre cohort study to determine the comparative effectiveness of these two drugs.
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一项“真实世界”回顾性多中心队列研究比较英夫利昔单抗和阿达木单抗维持溃疡性结肠炎缓解的疗效
抗肿瘤坏死因子治疗是治疗中度至重度活动性溃疡性结肠炎(UC)的常用方法。最近对对照试验数据的网络meta分析表明静脉注射药物(英夫利昔单抗)优于皮下注射药物(阿达木单抗)。我们进行了一项回顾性多中心队列研究,以确定这两种药物的比较有效性。
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