Comparative Safety Profiles of Pure and Alcohol Beverages in Wistar Rats

O. Dawodu, O. Ebuehi, O. Odesanmi
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引用次数: 1

Abstract

Objective: Alcohol consumption is readily acceptable worldwide, and despite warnings and billions of dollars spent yearly on its the present copious of The study investigated the comparative effects of pure and alcoholic on Wistar rats to in treatment compared GGT and activities of the treatment rat organ photomicrographs showed followed by the liver, kidney and brain. The GC-MS chromatograms of the respective beverages contained the following: beer 19, red wine 10 and spirit 16 constituents. Conclusion: The plasma ALT, AST, GGT activities however, did not indicate excess alcohol consumption in the animals although unusual values were observed. The histological profile on the rat organs showed that there was some form of organ damage implying that these beverages may be injurious to health. In addition, the GC-MS spectroscopy revealed that these alcoholic beverages had different proportions of the chemical constituents which may portend some futuristic threat to health.
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纯饮料和酒精饮料对Wistar大鼠的安全性比较
目的:酒精消费在世界范围内是可以接受的,尽管有警告和每年数十亿美元的花费,但目前大量的研究调查了纯酒精和酒精对Wistar大鼠的比较作用,在治疗中比较了GGT和治疗大鼠器官的活动,显微照片显示,其次是肝脏,肾脏和大脑。各饮料的GC-MS色谱包含以下成分:啤酒19,红酒10和烈酒16。结论:血浆ALT、AST、GGT活性虽有异常值,但未提示动物饮酒过量。对大鼠器官的组织学分析显示存在某种形式的器官损伤,这意味着这些饮料可能对健康有害。此外,气相色谱-质谱分析显示,这些酒精饮料的化学成分比例不同,这可能预示着未来对健康的威胁。
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