Economic Development, the Nutrition Trap and Metabolic Disease

N. Luke, Kaivan Munshi, A. Oommen, Swapnil Singh
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引用次数: 5

Abstract

This research provides a single explanation for: (i) the persistence of malnutrition and (ii) the increased prevalence of metabolic disease (diabetes, hypertension, cardiovascular disease) among normal weight individuals with economic development. Our model is based on a set point for BMI or bodyweight that is adapted to conditions of scarcity in the pre-modern economy, but which subsequently fails to adjust to rapid economic change. During the process of development, some individuals thus remain at their low-BMI set point, despite the increase in their consumption, while others who have escaped the nutrition trap (but are not necessarily overweight) are at increased risk of metabolic disease. The model and the underlying biological mechanism, which are validated with micro-data from India, Indonesia and Ghana can jointly explain inter-regional (Asia-Africa) differences in nutritional status and the prevalence of diabetes.
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经济发展、营养陷阱和代谢性疾病
这项研究提供了一个单一的解释:(i)营养不良的持续存在和(ii)随着经济发展,正常体重的个体中代谢性疾病(糖尿病、高血压、心血管疾病)的患病率增加。我们的模型基于BMI或体重的设定值,该设定值适应了前现代经济中物质匮乏的条件,但随后却无法适应快速的经济变化。因此,在发育过程中,尽管一些人的摄入量增加,但他们仍保持在低bmi设定点,而其他逃脱了营养陷阱(但不一定超重)的人患代谢性疾病的风险增加。印度、印度尼西亚和加纳的微观数据验证了该模型及其潜在的生物学机制,可以共同解释亚洲-非洲地区营养状况和糖尿病患病率的差异。
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