U. Zissler, Aljoscha Thron, J. Eckrich, S. Bakhtiar, R. Schubert, S. Zielen
{"title":"Bronchial inflammation biomarker patterns link humoral immunodeficiency with bronchiectasis‐related small airway dysfunction","authors":"U. Zissler, Aljoscha Thron, J. Eckrich, S. Bakhtiar, R. Schubert, S. Zielen","doi":"10.1111/cea.14140","DOIUrl":null,"url":null,"abstract":"The progression of chronic destructive lung disease in patients with humoral immunodeficiency (ID) and concomitant development of bronchiectasis is difficult to prevent. Lung function tests in these patients typically show bronchial obstruction of the small airways in combination with increased air trapping in the distal airways, which is consistent with small airway dysfunction.","PeriodicalId":10148,"journal":{"name":"Clinical & Experimental Allergy","volume":"84 1","pages":"760 - 773"},"PeriodicalIF":0.0000,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical & Experimental Allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/cea.14140","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The progression of chronic destructive lung disease in patients with humoral immunodeficiency (ID) and concomitant development of bronchiectasis is difficult to prevent. Lung function tests in these patients typically show bronchial obstruction of the small airways in combination with increased air trapping in the distal airways, which is consistent with small airway dysfunction.