The role of quercetin in the treatment of liver diseases: the review based on experimental and clinical investigations

V. Prysyazhnyuk, B. Senyuk, O. Glubochenko, P. Prysyazhnyuk, O. Bukach
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Abstract

Scientific review covers current data regarding the role of quercetin in the therapeutic corrections of various liver diseases, in particular non-alcoholic fatty liver disease, chronic hepatitis, drug-induced liver disease. The aim of the review was to sum up current scientific data regarding quercetin properties, its mechanism of action and possibilities of this flavonoid in the treatment of various liver diseases.Conclusions. Quercetin is found to possess antioxidant, anti-inflammatory, hypolipidemic, antisteatotic and antifibrotic properties. The abovementioned makes this flavonoid potentially useful in the treatment of various liver disease, in particular non-alcoholic fatty liver disease, chronic hepatitis of different etiologies, and drug induced liver disease.
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槲皮素在肝脏疾病治疗中的作用:基于实验和临床研究的综述
科学审查涵盖了有关槲皮素在各种肝脏疾病,特别是非酒精性脂肪性肝病、慢性肝炎、药物性肝病的治疗纠正中的作用的当前数据。本文综述了槲皮素的性质、作用机制以及槲皮素类黄酮治疗各种肝脏疾病的可能性。槲皮素被发现具有抗氧化、抗炎、降血脂、抗脂肪变性和抗纤维化的特性。上述情况使得这种类黄酮在治疗各种肝脏疾病,特别是非酒精性脂肪性肝病、不同病因的慢性肝炎和药物引起的肝脏疾病中具有潜在的用途。
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