An improved simple, robust, cheap and potential diagnostic device for Lead(II)

R. Sharmaa, P. Choukseya, S. Amlatheb
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Abstract

Environmental pollution and its consequences are of global concern. There is an urgent need of development of simple, low-cost detection or diagnostic point of care devices to detect, analyze and determine the pollutants in various environmental, food and biological samples. Such development will be critically important for improvisation of human health and quality of life. Toxic heavy metals potential contaminates and has lethal effects on deterioration of environment and thereby on human health. Paper based analytical sensors are an efficient diagnostic point-of-care devices being cheap, robust, user friendly and environmental-friendly. We have proposed a paper-based sensor for detection and quantitative determination of Lead by immobilization of potassium iodide and ninhydrin over paper platform. A bright yellow colour of varying intensity develops on coming in contact with samples contaminated with lead. The coloured area is then scanned and images are transferred to image processing tool of MATLAB software to read their RGB values. The effective intensities are then calculated mathematically. The developed sensor determines the contamination of lead up to 0.01 ppm. Thus, the proposed paper based analytical sensor is potential diagnostic point –of-care device.
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一种改进的简单、坚固、廉价和有潜力的铅(II)诊断装置
环境污染及其后果是全球关注的问题。迫切需要开发简单,低成本的检测或诊断护理点设备来检测,分析和确定各种环境,食品和生物样品中的污染物。这种发展对改善人类健康和生活质量至关重要。有毒重金属可能污染环境并对环境恶化造成致命影响,从而影响人类健康。基于纸张的分析传感器是一种高效的诊断点护理设备,价格便宜,坚固耐用,用户友好和环保。我们提出了一种用碘化钾和茚三酮固定在纸平台上的检测和定量测定铅的纸基传感器。与铅污染的样品接触时,会产生不同强度的亮黄色。然后扫描上色区域,将图像传输到MATLAB软件的图像处理工具中读取其RGB值。然后用数学方法计算有效强度。开发的传感器可测定高达0.01 ppm的铅污染。因此,提出的基于纸张的分析传感器是潜在的诊断护理点设备。
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6-12 weeks
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