Lithiase urinaire de l’enfant

M.-F Gagnadoux (Praticien hospitalier)
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引用次数: 5

Abstract

Urolithiasis is not uncommon in children and must be looked for with ultrasonography in any case of pyuria, hematuria or abdominal pain. By means of precise analysis of stone composition or, failing stone, of urines, an etiology can be found in approximately 80 % of child lithiases. In younger children, the two main causes are infection due to urease-producing bacteria, associated or not with urinary tract malformations, and metabolic disorders induced by prematurity and treatment of its complications (furosemide, steroids). In older children, metabolic disorders, particularly those due to inherited diseases, account for the majority of stones : hypercalciurias, secondary, iatrogenic or idiopathic, hyperoxalurias, primary (inherited), secondary, or “mild idiopathic”, cystinuria, hyperuricosurias, inherited or secondary, and other purine excretion disorders. Prevention of stone recurrence, essential in case of underlying metabolic disorder, always requires an abundant water intake (1.5-2 l/m2/day) associated with specific treatment of the causal disease if possible. If a surgical treatment is necessary, extra corporeal shock-wave lithotripsy is the first option like in adults.

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小儿尿石症
尿石症在儿童中并不罕见,在任何脓尿、血尿或腹痛的情况下都必须用超声检查。通过对结石成分或尿液的精确分析,可以在大约80%的儿童结石中找到病因。在较年幼的儿童中,两个主要原因是由产脲酶细菌引起的感染,与尿路畸形有关或无关,以及早产引起的代谢紊乱及其并发症(速尿、类固醇)的治疗。在年龄较大的儿童中,代谢性疾病,特别是遗传性疾病,是结石的主要原因:继发性、医源性或特发性高钙尿症、原发性(遗传性)、继发性或“轻度特发性”高草酸尿症、胱氨酸尿症、高尿酸尿症、遗传性或继发性以及其他嘌呤排泄障碍。预防结石复发对潜在的代谢紊乱至关重要,总是需要充足的水摄入量(1.5-2 l/m2/天),并在可能的情况下对病因进行特异性治疗。如果需要手术治疗,像成人一样,额外的身体冲击波碎石是第一选择。
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