The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia

IF 2.6 Q3 IMMUNOLOGY International Journal of Inflammation Pub Date : 2016-02-07 DOI:10.1155/2016/7802957
Mohammad H. Al-Hemairi, S. Albokhari, M. Muzaffer
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引用次数: 28

Abstract

Introduction. Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children. Our aim is to describe demographic, clinical, and laboratory characteristics and treatment of JIA patients followed up in Pediatric Rheumatology clinic in a tertiary center in Saudi Arabia. Methods. Medical records of all patients who are followed up between January 2007 and January 2015 were retrospectively reviewed. Data were collected about demographic, clinical, and laboratory features and treatment. Results. Total patients were 82, males were 31 (37.8%), and mean age of JIA onset was 7.1 ± 3.6 yr. Mean follow-up duration was 2.67±1.6 yr. Systemic onset JIA (SoJIA) was the commonest (36.5%), followed by polyarticular in 29.2% and oligoarticular in 28%. Large and small joints are involved in 76 (92%) and 30 (36.6%), respectively. Main extra-articular feature was fever in 34 (41.4%). Uveitis was diagnosed in 7 (8.5%) and in 5 (21.7%) of oligoarticular JIA. Anemia was found in 49 (59.7%), high ESR in 45 (54.8%), and leukocytosis and thrombocytosis in 33 (40.2%). Positive ANA was found in 30 (36.5%) mainly in oligoarticular subtype as 12 (52%) patients (out of 23) had this positive test. 9 patients (10.9%) required NSAIDs only, 6 patients (7.3%) required NSAIDs and intra-articular steroids only, and 19 (23%) required NSAIDs, methotrexate, steroids, and biologics. Conclusion. SoJIA is the most common JIA subtype in our study. A population based rather than a single center study will give more details about JIA characteristics in Saudi Arabia
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沙特阿拉伯单一三级中心的青少年特发性关节炎的模式
介绍。幼年特发性关节炎(JIA)是儿童中最常见的慢性关节炎。我们的目的是描述在沙特阿拉伯三级中心儿童风湿病诊所随访的JIA患者的人口学、临床和实验室特征和治疗。方法。回顾性分析2007年1月至2015年1月期间随访的所有患者的医疗记录。收集有关人口统计学、临床、实验室特征和治疗的数据。结果。总病例82例,男性31例(37.8%),JIA平均发病年龄为7.1±3.6年,平均随访时间为2.67±1.6年。全身性JIA (SoJIA)最常见(36.5%),其次是多关节性(29.2%)和少关节性(28%)。大关节76例(92%),小关节30例(36.6%)。34例(41.4%)以发热为主要关节外特征。7例(8.5%)和5例(21.7%)被诊断为葡萄膜炎。贫血49例(59.7%),高ESR 45例(54.8%),白细胞增多和血小板增多33例(40.2%)。ANA阳性30例(36.5%),主要发生在寡关节亚型,其中12例(52%)患者(23例)检测呈阳性。9例(10.9%)患者仅需要使用非甾体抗炎药,6例(7.3%)患者仅需要使用非甾体抗炎药和关节内类固醇,19例(23%)患者需要使用非甾体抗炎药、甲氨蝶呤、类固醇和生物制剂。结论。SoJIA是我们研究中最常见的JIA亚型。基于人群而非单中心的研究将提供沙特阿拉伯JIA特征的更多细节
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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
16
审稿时长
16 weeks
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